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- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
FITC
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
O75182
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
/
- 浓度:
>95%,Protein G purified
- 靶点:
SIN3B
- 抗体英文名:
SIN3B Antibody, FITC conjugated
- 抗体名:
SIN3B antibody;KIAA0700 antibody;Paired amphipathic helix protein Sin3b antibody;Histone deacetylase complex subunit Sin3b antibody;Transcriptional corepressor Sin3b antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Transgenic Targeting of a Dominant Negative Corepressor to Liver and Analyses by cDNA Microarray
and three transferable repression domains in the amino terminus (RD1, RD2, RD3 ) (3 ,6 ). RD1 and a region downstream of RD3 have been shown to recruit histone deacetylases (HDAC1 and HDAC2 ) through direct interaction with Sin3B (3 ,6 -9 ). The TR/corepressor/sin3
antibody 抗体类型:兔多抗 验证图片: 3.K006153P Anti-β-actin Polyclonal Antibody 抗体类型:兔多抗 验证图片: 4.K011709RR Anti-β Actin Recombinant Antibody 抗体类型:重组兔单抗 验证图片: 5.K118491P Anti-β-actin Polyclonal Antibody 抗体类型:兔多抗 验证图片: 6.K112355P Anti-β-actin Polyclonal Antibody
:分别是竞争性蛋白质结合分析法[3]、放射性免疫分析法[4]和薄层色谱法[5]。在80年代,放射性免疫分析法得到了广泛的应用和改进,由于这种方法采用放射性核素标记,应用范围受到一定限制,为了进一步提高检测的灵敏度和操作的安全性,进入90年代又陆续发明了各种酶标记法和化学发光法的竞争性ELISA检测试剂盒,这一类检测方法的根本原理都是基于抗体抗原的免疫反应,所有这些试剂盒中采用的抗体全部是兔抗血清或者是经过特异亲和提纯之后的抗cAMP或cGMP的兔多抗,毫无疑问,兔多抗在约四十年的cAMP,cGMP定量
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