- ￥1175 - 39097
- PeproTech
- USA
- 100-36E-100UG
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
3years
- 英文名：
Recombinant Human TGF-beta3
- 库存：
少量现货
- 供应商：
Neobioscience
- 保存条件：
-20°C
- 规格：
2ug/10 ug/100 ug/250 ug/50 ug
| 规格： | 2ug | 产品价格： | ￥1175.0 |
|---|---|---|---|
| 规格： | 10 ug | 产品价格： | ￥2864.0 |
| 规格： | 100 ug | 产品价格： | ￥22359.0 |
| 规格： | 250 ug | 产品价格： | ￥39097.0 |
| 规格： | 50 ug | 产品价格： | ￥13401.0 |
Human TGF-beta 3 Recombinant Protein, PeproTech® 产品货号100-36E，有多种规格可供选择。
产品详细信息
Recombinant Human TGF-beta3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
Transforming growth factor beta 3 (TGF beta 3) is the third member of the transforming growth factor family of cytokines, which also includes TGF beta 1 and beta 2. These cytokines are secreted in precursor form consisting of a bioactive C-terminal domain attached to an N-terminal domain known as latency associated protein (LAP). Cleavage of LAP results in the mature protein, which functions as a disulfide-linked homodimer. As with all members of the family, TGF beta 3 is highly conserved across species, with mouse and human TGF beta 3 demonstrating 100% sequence homology and cross-species activity.The members of this family can be expressed by most cell types and exert pleiotropic effects, which include the suppression of B- and T-cell effector activity, mediation of tissue healing, and suppression of tumor proliferation. The promotion of CD4+CD25+ T-cell expansion is a newly discovered function of the TGF beta cytokines, and indicates an important role in the protection against autoimmunity.
产品信息
免疫印迹 (WB)
酶联免疫吸附实验 (ELISA)
功能检测 (Functional)
体外检测 (IV)
其他PubMed (Misc)
免疫染色 (IS)
Surface plasmon resonance (SPR)
种属
已发表种属
Expression System
氨基酸序列
分子量
分类
类型
纯度
内毒素浓度
活性
偶联物
形式
纯化类型
内含物
保存条件
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文献和实验Oncotarget
TGF-ß isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity.
"100-36E was used in Sample Preparation (Western Blotting) to investigate the main TGF-ß signalling pathway across 13 different tumour types."
Authors Riemenschneider MJ,Hirblinger M,Vollmann-Zwerenz A,Hau P,Proescholdt MA,Jaschinski F,Rothhammer-Hampl T,Wosikowski K,Janicot M,Leo E
Cell & bioscience
Generation of musculoskeletal cells from human urine epithelium-derived presomitic mesoderm cells.
"100-36E was used in In vitro experiments to find that UiPSM and myoblast determination protein 1 mediated UiPSM cell-derived skeletal myocytes were viable after transplantation into the tibialis anterior muscle of MITRG mice."
Authors Gao H,Huang X,Cai Z,Cai B,Wang K,Li J,Kuang J,Wang B,Zhai Z,Ming J,Cao S,Qin Y,Pei D
Drug delivery and translational research
Sleeping Beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson's disease.
"100-36E was used in In vitro experiments to establish a promising GDNF treatment system in a PD model."
Authors Stahn L,Rasińska J,Dehne T,Schreyer S,Hakus A,Gossen M,Steiner B,Hemmati-Sadeghi S
Construction of Recombinant Human Cytomegalovirus
The use of reverse genetics to generate recombinant viruses allows the researcher to investigate the exact functional significance of particular viral genes during the virus life cycle, by means of their deletion or modification in the viral
Delivery of Recombinant Adenoviruses to Human Saphenous Vein
The human saphenous vein is the most commonly used conduit for coronary artery bypass grafting owing to its ready availability, ease of harvesting, and favorable surgical handling (1 ). However, it suffers from a progressive decline
Recombinant Genetic Libraries and Human Monoclonal Antibodies
In order to comprehensively manipulate the human proteome we require a vast repertoire of pharmacological reagents. To address these needs we have developed repertoires of synthetic antibodies by phage display, where diversified
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