重组人白介素15,Recombinant Human Interleukin-15
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重组人白介素15,Recombinant Human Int

erleukin-15
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  • ¥2870
  • peprotech
  • 200-15-10UG
  • ProSpec
  • 2025年08月03日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      大量

    • 供应商

      200-15-10UG

    • 英文名

      Recombinant Human Interleukin-15

    • 规格

      10μg

    重组人白介素15,Recombinant Human Interleukin-15
    货号:200-15-10ug

    IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.  IL-15 exerts its biological activities primarily on T cells.  It is also essential in the development, survival and activation of NK cells.  Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I.  Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.  Recombinant Human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.

    Source: E.coli

     

     

    Synonyms: Interleukin-15, IL-T

     

     

    AA Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS

     

     

    Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

     

     

    Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells was found to be ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

    This product has been tested against the WHO standard. International Unit information can be found here.

    Recombinant Human IL-15 WHO Comparison Graph Recombinant Human IL-15 Biological Activity Graph

     

    Calculated Molecular Weight: 12.9 kDa

     

     

    Accession Number: P40933

     

     

    Gene ID: 3600

     

     

    Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

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    图标文献和实验
    该产品被引用文献

    product.subtitle.recentcitations

    第一作者
    Wang, W
    标题
    Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors.
    文献引用
    Advanced science (Weinheim, Baden-Wurttemberg, Germany); 9(22) pge2105810
    PubMed Id
    第一作者
    Moosmann, C
    标题
    Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair.
    文献引用
    STAR Protocols; 3(1) pg101031
    PubMed Id
    第一作者
    Matis, S
    标题
    LINC00152 expression in normal and Chronic Lymphocytic Leukemia B cells.
    文献引用
    Hematological Oncology; 40(1) pg40-47
    PubMed Id
    34679195
    现有评论
    CD8 stimulation culture
     
    When used at 10 ng/mL, it promoted the survival and expansion of human CD8+ T cells. Cells were stimulated with anti-CD3/anti-CD28 for 2 days in the presence of rhIL-15 and then expanded for 6 days in the presence of rhIL-15 alone.
    来自:  Michael | 日期:  2023/8/8
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