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Human R-Spondin 1 Recombinant

Protein
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  • ￥18888
  • GIBCO已认证
  • 120-38-500
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  • 2025年08月05日
    48h发货
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    • 库存：

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    • 英文名：

      Human R-Spondin 1 Recombinant Protein

    • 规格：

      500μg

    Human R-Spondin 1 Recombinant Protein(500 µg)

    产品细节图片1

    产品细节图片2

    产品细节图片3

    Product Details

    Size

    500 µg

    Species

    Human

    Published Species

    Dog, Pig, Bovine, Mouse, Human, Xenopus

    Expression system

    CHO cells

    Amino acid sequence

    SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP

    PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM

    ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT   VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA

    Molecular weight

    26.7 kDa

    Class

    Recombinant

    Type

    Protein

    Purity

    95% by SDS-PAGE gel and HPLC analyses.

    Endotoxin concentration

    <1 EU/µg

    Activity

    R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml.

    Conjugate

    Unconjugated

    Form

    Lyophilized

    Purification

    purified

    Contains

    no preservative

    Storage conditions

    -20°C

     

    Applications

    Tested Dilution

    Publications

    Immunohistochemistry (IHC)

    -

    1 Publication

    Functional Assay (Functional)

    Assay-dependent

    -

    In vitro Assay (IV)

    -

    59 Publications

    Miscellaneous PubMed (Misc)

    -

    18 Publications

     

     

    Product Specific Information

    120-38-1MG will be provided as 2 x 500 µg (120-38-500UG).

    Recombinant Human R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R- Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions.

    This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis

    产品细节图片4

    Human R-Spondin 1 Protein (120-38-500UG) in Functional
    Bioassay analysis of Human R-Spondin 1 Recombinant Protein, PeproTech® (Product # 120-38-1MG).

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      图标文献和实验
      该产品被引用文献

      [1]Ekanger CT, Zhou F, Bohan D, Lotsberg ML, Ramnefjell M, Hoareau L, Røsland GV, Lu N, Aanerud M, Gärtner F, Salminen PR, Bentsen M, Halvorsen T, Ræder H, Akslen LA, Langeland N, Cox R, Maury W, Stuhr LEB, Lorens JB, Engelsen AST. Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus. Front Cell Infect Microbiol. 2022 Mar 14;12:841447. doi: 10.3389/fcimb.2022.841447. PMID: 35360113; PMCID: PMC8964279.

      [2]Molinuevo R, Menendez J, Cadle K, Ariqat N, Choy MK, Lagousis C, Thomas G, Strietzel C, Bubolz JW, Hinck L. Physiological DNA damage promotes functional endoreplication of mammary gland alveolar cells during lactation. Nat Commun. 2024 Apr 17;15(1):3288. doi: 10.1038/s41467-024-47668-9. PMID: 38627401; PMCID: PMC11021458.

      [3]Liu F, Lin Q, Shen S, Li Z, Xie X, Cheng Q, Wang L, Long Y, Wang J, Liu L. Secretion of WNT7A by UC-MSCs assist in promoting the endometrial epithelial regeneration. iScience. 2024 May 3;27(6):109888. doi: 10.1016/j.isci.2024.109888. PMID: 38947517; PMCID: PMC11214297.

      [4]Pereira VM, Pinto PAF, Motta LCB, Almeida MF, de Andrade AFC, Pavaneli APP, Ambrósio CE. Initial Characterization of 3D Culture of Yolk Sac Tissue. Animals (Basel). 2023 Apr 22;13(9):1435. doi: 10.3390/ani13091435. PMID: 37174472; PMCID: PMC10177165.

      [5]Nakamura K, Reid BM, Chen A, Chen Z, Goode EL, Permuth JB, Teer JK, Tyrer J, Yu X, Kanetsky PA, Pharoah PD, Gayther SA, Sellers TA, Lawrenson K, Karreth FA. Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer. Am J Hum Genet. 2022 Jan 6;109(1):116-135. doi: 10.1016/j.ajhg.2021.11.020. Epub 2021 Dec 28. PMID: 34965383; PMCID: PMC8764204.

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      Human R-Spondin 1 Recombinant Protein
      ￥18888