RBM20 RNA结合蛋白20抗体

RBM20 RNA结合蛋白20抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-9606R
  • 进口/国产
  • 2025年11月17日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
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    • 详细信息
    • 询价记录
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-9606R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      RBM20

    • 抗体名

      RNA结合蛋白20抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Cow, Horse, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human RBM20:361-460/1227

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    RBM20 RNA结合蛋白20抗体
    英文名称 RBM20
    中文名称 RNA结合蛋白20抗体
    别    名 Probable RNA-binding protein 20; Rbm20; RBM20_HUMAN; RNA-binding motif protein 20.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 心血管  转录调节因子  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 134kDa
    细胞定位 细胞核 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human RBM20:361-460/1227 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    This gene encodes a protein that likely binds RNA. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Mar 2010]

    Function:
    RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin). 

    Subcellular Location:
    Nucleus (By similarity). 

    Tissue Specificity:
    Expressed in the heart.

    DISEASE:
    Defects in RBM20 are the cause of cardiomyopathy dilated type 1DD (CMD1DD) [MIM:613172]. A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. 

    Similarity:
    Contains 1 RRM (RNA recognition motif) domain.

    SWISS:
    Q5T481

    Gene ID:
    282996

    Database links:

    Entrez Gene: 282996 Human

    Entrez Gene: 73713 Mouse

    Entrez Gene: 309544 Rat

    Omim: 613171 Human

    SwissProt: Q5T481 Human

    SwissProt: Q3UQS8 Mouse

    Unigene: 92105 Cow

    Unigene: 116630 Human

    Unigene: 726550 Human

    Unigene: 485879 Mouse

    Unigene: 21596 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    Involvement in disease;Defects in RBM20 are the cause of cardiomyopathy dilated type 1DD (CMD1DD). A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    产品图片 RBM20 RNA结合蛋白20抗体
    Sample: heart (mouse) Lysate at 40 ug
    Primary: Anti- RBM20 (bs-9606R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 75kD
    Observed band size: 75 kD

    RBM20 RNA结合蛋白20抗体
    Tissue/cell: mouse embryo tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
    Incubation: Anti-RBM20 Polyclonal Antibody, Unconjugated(bs-9606R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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