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碱性成纤维细胞生长因子bFGF

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  • 100-18B
  • 美国
  • 2025年12月13日
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 英文名

      Recombinant Human FGF-basic (154 a.a.)

    • 供应商

      上海研卉生物科技有限公司

    • 库存

      大量

    • 规格

      10ug

    碱性成纤维细胞生长因子bFGF

    Recombinant Human FGF-basic (154 a.a.)

    Product Details

    Catalog Number: 100-18B
    Description:

    FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
    Qualified for stem cell use.

    Source: E.coli

    Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

    AA Sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

    Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

    Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

    Calculated Molecular Weight: 17.2 kDa

    Accession Number: P09038

    Gene ID: 2247

    Cross Reactivity:
    Alpaca, Bacteria, Chicken, Cow, Dog, Frog, Hamster, Horse, Human , Human + Hamster, Human + Mouse, Human + Rat, Human + Virus, Monkey, Mouse, Mouse + Chicken, Mouse + Pig, Mouse + Rat, N/A, Pig, Rabbit, Rat, Rat + Chicken, Sheep, Trout
    部分引用文献:
    First Author Title Citation Date Pubmed
    Milleret, V Rational design and in vitro characterization of novel dental implant and abutment surfaces for balancing clinical and biological needs. ACS Medicinal Chemistry Letters; 21 Suppl 1 pg15-24 1 Mar 2019 30809940
    Show Usages
    Rosa, S Functional characterization of iPSC-derived arterial- and venous-like endothelial cells. ACS Medicinal Chemistry Letters; 9(1) pg3826 7 Mar 2019 30846769
    Show Usages
    Misawa, T Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains. Acta Neuropathologica; 116(3) pg247-60 0 Sep 2008 18509662
    Show Usages
    Brett, J O The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging; 3(2) pg108-24 0 Feb 2011 21386132
    Show Usages
    Bogomazova, A N Error-prone nonhomologous end joining repair operates in human pluripotent stem cells during late G2. Aging; 3(6) pg584-96 0 Jun 2011 21685510
    Show Usages
    Brazel, C Y Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain. Aging Cell; 4(4) pg197-207 0 Aug 2005 16026334
    Show Usages
    Liu, S The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro. Aging Cell; 10(4) pg661-74 0 Aug 2011 21418510
    Show Usages
    Mohan, S High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction. American Journal of Physiology. Cell Physiology; 296(1) pgC182-92 0 Jan 2009 18945937
    Show Usages
    Cocks, H C Role and regulation of the fibroblast growth factor axis in human thyroid follicular cells. American Journal of Physiology. Endocrinology and Metabolism; 285(3) pgE460-9 0 Sep 2003 12746216
    Show Usages
    Chailley-Heu, B FGF-18 is upregulated in the postnatal rat lung and enhances elastogenesis in myofibroblasts. American Journal of Physiology. Lung Cellular and Molecular Physiology; 288(1) pgL43-51 0 Jan 2005 15447937
    Show Usages
    Tamò, L Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology; 315(6) pgL921-L932 1 Dec 2018 30211653
    Show Usages
    Trapp, V Anti-angiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture. Angiogenesis; 13(4) pg305-15 0 Dec 2010 20927579
    Show Usages
    Cass, W A Protection by GDNF and other trophic factors against the dopamine-depleting effects of neurotoxic doses of methamphetamine. Annals of the New York Academy of Sciences; 1074 pg272-81 0 Aug 2006 17105923
    Show Usages
    Scharbrodt, W Basic fibroblast growth factor-induced endothelial proliferation and NO synthesis involves inward rectifier K+ current. Arteriosclerosis, Thrombosis, and Vascular Biology; 24(7) pg1229-33 0 Jul 2004 15130912
    Show Usages
    Vincent, T L Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded. Arthritis and Rheumatism; 50(2) pg526-33 0 Feb 2004 14872495
    Show Usages
    Nakano, K Induction of RANKL expression and osteoclast maturation by the binding of fibroblast growth factor 2 to heparan sulfate proteoglycan on rheumatoid synovial fibroblasts. Arthritis and Rheumatism; 50(8) pg2450-8 0 Aug 2004 15334457
    Show Usages
    Sawaji, Y Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage. Arthritis and Rheumatism; 58(11) pg3498-509 0 Nov 2008 18975307
    Show Usages
    Guardia Clausi, M Apotransferrin-induced recovery after hypoxic/ischaemic injury on myelination. ASN Neuro; 2(5) pge00048 19 Nov 2010 21113232
    Show Usages
    Yanagisawa, M Expression of GD2 and GD3 gangliosides in human embryonic neural stem cells. ASN Neuro; 3(2) 7 Apr 2011 21395555
    Show Usages
    Wang, X FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12-ATG5 conjugate, leading to the delay of cartilage development in achondroplasia. Autophagy; 11(11) pg1998-2013 2 Nov 2015 26491898
    Show Usages
    Penvose, A Sca-1 is involved in the adhesion of myosphere cells to αVβ3 integrin. Biology Open; 1(9) pg839-47 15 Sep 2012 23213478
    Show Usages
    Freeman, I The influence of the sequential delivery of angiogenic factors from affinity-binding alginate scaffolds on vascularization. Biomaterials; 30(11) pg2122-31 0 Apr 2009 19152972
    Show Usages
    Pabbruwe, M B Induction of cartilage integration by a chondrocyte/collagen-scaffold implant. Biomaterials; 30(26) pg4277-86 0 Sep 2009 19539365
    Show Usages
    Khan, I M In vitro growth factor-induced bio engineering of mature articular cartilage. Biomaterials; 34(5) pg1478-87 0 Feb 2013 23182922
    Show Usages
    Gaviraghi, M Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells. Bioscience Reports; 31(1) pg45-55 0 Feb 2011 20426768
    Show Usages
    Ramalingam, R E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells. Blood; 93(9) pg2936-44 1 May 1999 10216088
    Show Usages
    Collen, A Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix. Blood; 101(5) pg1810-7 1 Mar 2003 12393408
    Show Usages
    Marodon, G Specific transgene expression in human and mouse CD4+ cells using lentiviral vectors with regulatory sequences from the CD4 gene. Blood; 101(9) pg3416-23 1 May 2003 12511423
    Show Usages
    Peng, H Identification of a binding site on human FGF-2 for fibrinogen. Blood; 103(6) pg2114-20 15 Mar 2004 14630795
    Show Usages
    Ingram, D A Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood; 104(9) pg2752-60 1 Nov 2004 15226175
    Show Usages
    Sahni, A Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3. Blood; 104(12) pg3635-41 1 Dec 2004 15297314
    Show Usages
    Secchiero, P TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release. Blood; 105(9) pg3413-9 1 May 2005 15644410
    Show Usages
    Ulyanova, T VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin. Blood; 106(1) pg86-94 1 Jul 2005 15769895
    Show Usages
    Zhou, H T cell-mediated suppression of angiogenesis results in tumor protective immunity. Blood; 106(6) pg2026-32 15 Sep 2005 15920006
    Show Usages
    Zijlstra, A Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells. Blood; 107(1) pg317-27 1 Jan 2006 16174763
    Show Usages
    Anjos-Afonso, F Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment. Blood; 109(3) pg1298-306 1 Feb 2007 17003364
    Show Usages
    Tober, J The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood; 109(4) pg1433-41 15 Feb 2007 17062726
    Show Usages
    Nakayama, T FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood; 109(4) pg1363-72 15 Feb 2007 17077327
    Show Usages
    Nagano, M Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood; 110(1) pg151-60 1 Jul 2007 17379743
    Show Usages
    Davis, R P Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors. Blood; 111(4) pg1876-84 15 Feb 2008 18032708
    Show Usages
    Zambidis, E T Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells. Blood; 112(9) pg3601-14 1 Nov 2008 18728246
    Show Usages
    Carmona, G Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. Blood; 113(2) pg488-97 8 Jan 2009 18805968
    Show Usages
    Klimchenko, O A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis. Blood; 114(8) pg1506-17 20 Aug 2009 19478046
    Show Usages
    Kovarova, M Human embryonic stem cells: a source of mast cells for the study of allergic and inflammatory diseases. Blood; 115(18) pg3695-703 6 May 2010 20200352
    Show Usages
    Yu, C Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell-derived hemato-vascular precursors. Blood; 116(23) pg4786-94 2 Dec 2010 20427702
    Show Usages
    Taylor, S M Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels. Blood; 116(16) pg3108-17 21 Oct 2010 20664058
    Show Usages
    El Haddad, N Mesenchymal stem cells express serine protease inhibitor to evade the host immune response. Blood; 117(4) pg1176-83 27 Jan 2011 21076046
    Show Usages
    Huang, X Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells. Blood; 117(7) pg2157-65 17 Feb 2011 21163928
    Show Usages
    Kumano, K Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. Blood; 119(26) pg6234-42 28 Jun 2012 22592606
    Show Usages
    Yu, Q C APELIN promotes hematopoiesis from human embryonic stem cells. Blood; 119(26) pg6243-54 28 Jun 2012 22611158
    Show Usages
    Amabile, G In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. Blood; 121(8) pg1255-64 21 Feb 2013 23212524
    Show Usages
    Merling, R K Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34+ cells. Blood; 121(14) pge98-107 4 Apr 2013 23386128
    Show Usages
    Gekas, C CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood; 121(22) pg4463-72 30 May 2013 23564910
    Show Usages
    Zhang, H Fibrocytes represent a novel MDSC subset circulating in patients with metastatic cancer. Blood; 122(7) pg1105-13 15 Aug 2013 23757729
    Show Usages
    Traer, E Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations. Blood; 123(10) pg1516-24 6 Mar 2014 24408322
    Show Usages
    Hsu, J Reprogramming identifies functionally distinct stages of clonal evolution in myelodysplastic syndromes. Blood; 134(2) pg186-198 11 Jul 2019 31010849
    Show Usages
    Wehr, M C Analysis of transient phosphorylation-dependent protein-protein interactions in living mammalian cells using split-TEV. BMC Biotechnology; 8 pg55 13 Jul 2008 18620601
    Show Usages
    Melotti, A In vitro and in vivo characterization of highly purified human mesothelioma derived cells. BMC Cancer; 10 pg54 22 Feb 2010 20175889
    Show Usages
    Amoureux, M Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines. BMC Cancer; 10 pg91 10 Mar 2010 20219118
    Show Usages
    Cohen, J R Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures. BMC Cancer; 10 pg676 9 Dec 2010 21143927
    Show Usages
    Martins-Neves, S R Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line. BMC Cancer; 12 pg139 4 Apr 2012 22475227
    Show Usages
    Monticone, M Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells. BMC Cancer; 12 pg358 17 Aug 2012 22901239
    Show Usages
    Põlajeva, J miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma. BMC Cancer; 12 pg378 29 Aug 2012 22931209
    Show Usages
    Põlajeva, J miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma. BMC Cancer; 12 pg378 29 Aug 2012 22931209
    Show Usages
    Ogaki, S An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. BMC Developmental Biology; 11 pg13 1 Mar 2011 21362171
    Show Usages
    Silber, J miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Medicine; 6 pg14 24 Jun 2008 18577219
    Show Usages
    Milner, R A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system. BMC Neuroscience; 8 pg3 2 Jan 2007 17199896
    Show Usages
    Borgs, L Period 2 regulates neural stem/progenitor cell proliferation in the adult hippocampus. BMC Neuroscience; 10 pg30 27 Mar 2009 19327139
    Show Usages
    Montague, P Subcellular localization of Mayven following expression of wild type and mutant EGFP tagged cDNAs. BMC Neuroscience; 11 pg63 26 May 2010 20504342
    Show Usages
    Mamaeva, D Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord. BMC Neuroscience; 12 pg99 10 Oct 2011 21985235
    Show Usages
    El-Akabawy, G Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington's disease. BMC Neuroscience; 13 pg97 9 Aug 2012 22876937
    Show Usages
    Hicks, S D Evaluation of cell proliferation, apoptosis, and DNA-repair genes as potential biomarkers for ethanol-induced CNS alterations. BMC Neuroscience; 13 pg128 25 Oct 2012 23095216
    Show Usages
    Techangamsuwan, S Similar behaviour and primate-like properties of adult canine Schwann cells and olfactory ensheathing cells in long-term culture. Brain Research; 1240 pg31-8 13 Nov 2008 18817757
    Show Usages
    Bajo, A M Bombesin antagonists inhibit proangiogenic factors in human experimental breast cancers. British Journal of Cancer; 90(1) pg245-52 12 Jan 2004 14710236
    Show Usages
    Mukherjee, A Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study. British Journal of Cancer; 92(2) pg350-8 31 Jan 2005 15655539
    Show Usages

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