TNFAIP3 interacting protein 3肿瘤坏死因子α诱导相互作用蛋白3抗体

TNFAIP3 interacting protein 3肿

瘤坏死因子α诱导相互作用蛋白3抗体
收藏
  • ¥1380 - 2200
  • LMAI Bio
  • LM-7551R
  • 进口/国产
  • 2025年12月17日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Cow, Sheep,
avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-7551R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      TNFAIP3 interacting protein 3

    • 抗体名

      肿瘤坏死因子α诱导相互作用蛋白3抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Cow, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3:51-150/325

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    TNFAIP3 interacting protein 3肿瘤坏死因子α诱导相互作用蛋白3抗体
    英文名称 TNFAIP3 interacting protein 3
    中文名称 肿瘤坏死因子α诱导相互作用蛋白3抗体
    别    名 Listeria induced; A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; ABIN-3 beta; FLJ21162; LIND; Listeria induced gene protein; TNFAIP3 interacting protein 3; TNFAIP3-interacting protein 3 beta; TNIP3; TNIP3 beta; TNIP3_HUMAN.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 心血管  染色质和核信号  信号转导  转录调节因子  内皮细胞  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Cow, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 39kDa
    细胞定位 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3:51-150/325 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.

    Function:
    Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. 

    Subunit:
    Interacts with TNFAIP3. Interacts with polyubiquitin. 

    Tissue Specificity:
    Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL. 

    SWISS:
    Q96KP6

    Gene ID:
    79931

    Database links:

    Entrez Gene: 79931 Human

    Entrez Gene: 414084 Mouse

    Omim: 608019 Human

    SwissProt: Q96KP6 Human

    Unigene: 208206 Human

    Unigene: 117558 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 TNFAIP3 interacting protein 3肿
    Sample: 
    Spleen (Mouse) Lysate at 40 ug
    Primary: Anti- TNFAIP3 interacting protein 3 (bs-7551R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 39 kD
    Observed band size: 39 kD

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥1380
    上海雅吉生物科技有限公司
    2025年07月11日询价
    ¥1680
    温州科淼生物科技有限公司
    2025年08月20日询价
    询价
    上海岑特生物科技有限公司
    2025年07月03日询价
    TNFAIP3 interacting protein 3肿瘤坏死因子α诱导相互作用蛋白3抗体
    ¥1380 - 2200