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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-5918R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
ANGPTL3
- 抗体名:
血管生成素样蛋白3抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Cow, Rabbit,
- 免疫原:
KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3:21-120/460
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | ANGPTL3 |
| 中文名称 | 血管生成素样蛋白3抗体 |
| 别 名 | ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; ANGPTL3; FHBL2. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 心血管 细胞生物 免疫学 信号转导 生长因子和激素 血管内皮细胞 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Rabbit, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3:21-120/460 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| PubMed | PubMed |
| 产品介绍 | background: Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes. Subcellular Location: Secreted Tissue Specificity: Expressed principally in liver. Weakly expressed in kidney. Similarity: Contains 1 fibrinogen C-terminal domain. SWISS: Q9Y5C1 Gene ID: 27329 Database links: Entrez Gene: 27329 Human Entrez Gene: 30924 Mouse Entrez Gene: 502970 Rat Omim: 604774 Human SwissProt: Q9Y5C1 Human SwissProt: Q9R182 Mouse Unigene: 209153 Human Unigene: 28341 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 | ![]() Sample: Hepg2(Human) Cell Lysate at 30 ug Primary: Anti-ANGPTL3 (bs-5918R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 59 kD |
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文献和实验人血管生成素样蛋白3(ANGPTL3)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人血管生成素样蛋白3 (ANGPTL3)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 ANGPTL3 单抗包被于酶标板上,标准品和样品中的 ANGPTL3与单抗结合,加入生物素化的抗人
试验结果,证实两种多肽能刺激机体产生特异性抗体和特异性细胞免疫,并有较好的安全性。我国清华大学也证实HIV-I膜蛋白内一段多肽有很强的免疫原性。丙肝病毒多肽疫苗也显示有良好的发展前景,国外学者从丙肝病毒(HCV)外膜蛋白E2内筛选出一般多肽,它可刺激机体产生保护性抗体。其它病毒(如甲肝、麻疹、辛德毕斯病毒等)的多肽疫苗及抗肿瘤,避孕等多肽疫苗的研究也取得了较大进展。例如,美国学者NaZ等从噬菌体肽库内筛选出一个12氨基酸小肽,它能特异性地与人卵子结合,阻止精子与卵子的结合,可用于避孕疫苗
排卵后由卵泡迅速转变成的富有血管的腺体样结构。如未受精形成的称月经黄体,如受精则为妊娠黄体。排卵后卵泡壁塌陷,颗粒层向内形成皱襞,伴有卵泡膜内层毛细血管出血,伤口愈后,卵泡腔封闭,腔内充满浆液性液体及血液,同时基膜崩溃,结缔组织和血管随之长入粒层,在黄体生成素作用下,颗粒细胞和卵泡膜内层细胞分裂增生,细胞成多边形,胞质内有黄色颗粒和脂滴,呈黄色,故名。黄体细胞以颗粒细胞占多数,细胞大,着色浅,分泌孕酮;泡膜黄体细胞小,大部位于黄体外周,细胞较少,核和质都较黄体细胞深,分泌
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