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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-1860R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
CRLR
- 抗体名:
降钙素基因相关肽1型受体抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat,
- 免疫原:
KLH conjugated synthetic peptide derived from human CGRPR1:281-380/461 <Cytoplasmic>
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:500-1000 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
50ul 100ul 200ul
| 英文名称 | CRLR |
| 中文名称 | 降钙素基因相关肽1型受体抗体 |
| 别 名 | CGRPR; calcitonin receptor like precursor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; CALCRL; CGRP type 1 receptor; CGRPR; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; Calcitonin Receptor Like Receptor; CALCRL; CGRP type 1 receptor; CALRL_HUMAN. |
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Specific References (1) | bs-1860R has been referenced in 1 publications. [IF=4.60] Toriyama, Yuichi, et al. "Pathophysiological Function of Endogenous Calcitonin Gene–Related Peptide in Ocular Vascular Diseases." The American Journal of Pathology (2015). Mouse. PubMed:25857228 |
| 规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul 200ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 信号转导 G蛋白偶联受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CGRPR1:281-380/461 <Cytoplasmic> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: CRLR is a receptor for calcitonin gene related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries. Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in the lung and heart. Similarity: Belongs to the G-protein coupled receptor 2 family. SWISS: Q16602 Gene ID: 10203 Database links: Entrez Gene: 10203 Human Entrez Gene: 54598 Mouse Entrez Gene: 397172 Pig Entrez Gene: 25029 Rat Entrez Gene: 527140 Cow Omim: 114190 Human SwissProt: Q16602 Human SwissProt: Q9R1W5 Mouse SwissProt: Q8WN93 Pig SwissProt: Q63118 Rat Unigene: 470882 Human Unigene: 11202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 | ![]() Sample: Lung (Mouse) Lysate at 30 ug Lymph(Mouse) Lysate at 30 ug Primary: Anti- CRLR (bs-1860R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD |
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