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- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-11307R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
Prostaglandin I2 Receptor
- 抗体名:
前列环素受体抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 免疫原:
KLH conjugated synthetic peptide derived from human Prostaglandin I2 Receptor:101-200/386 <Extracellular>
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | Prostaglandin I2 Receptor |
| 中文名称 | 前列环素受体抗体 |
| 别 名 | IP; PGI receptor; PGI2 receptor; PI2R_HUMAN; PRIPR; Prostacyclin receptor; Prostaglandin I2 receptor; Prostanoid IP receptor; PTGIR. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 心血管 细胞生物 信号转导 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Prostaglandin I2 Receptor:101-200/386 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2?, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G protein-coupled prostanoid receptors, designated EP, FP, IP, TP and DP, respectively. The IP Receptor binds prostacyclin, PGI2, the main pro-stanoid synthesized by vascular tissues.Upon binding to the IP Receptor, prostacyclin activates adenylate cyclase primarily through the Gas protein. The gene encoding the human IP Receptor is located on chromosome 19. It is expressed as a glycosylated and phosphorylated protein, which is abundantly expressed in vascular tissues such as aorta, lung, atrium and ventricle, as well as in kidney, thymus, spleen and neurons. Function: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. Subcellular Location: Cell membrane. Post-translational modifications: Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling. Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P43119 Gene ID: 5739 Database links: Entrez Gene: 5739 Human Omim: 600022 Human SwissProt: P43119 Human Unigene: 458324 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验新基因的全名在GDB数据库中没有出现过, 而且新基因符号的词根在GDB中也要没有出现过。如要命名一个基因为“PTGG1”, 虽然在GDB数据库中没有出现过“PTGG1”, 但“PTGG1”仍不能作为基因符号, 因为“PTG”已用于代表前列腺素(prostaglandin),用“PTGG1”将干扰已用“PTG”为头命名的基因系列: PTGDR ? 前列腺素D2受体基因 PTGDS 前列腺素D2合酶基因 PTGER1 前列腺素E受体1基因 PTGER2 前列腺素E受体2基因 PTGER3
receptor antibody 乙酰胆碱受体抗体 ACIF anti-complement immunofluorescent method 抗补体免疫荧光法 α-1-ACt alpha(α)-1-anti-chymotrypsin α-1-抗糜蛋白酶 ACTH adrenocorticotropin hormone 促肾上腺皮质激素 AD Alzheimer's disease 老年性痴呆 ADDC antibody dependent
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