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5HT1A Receptor 5-羟色胺受体1A抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-1124R
  • 进口/国产
  • 2025年07月12日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Dog, Horse, Rabbit, 
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-1124R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      5HT1A Receptor

    • 抗体名

      5-羟色胺受体1A抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Horse, Rabbit, 

    • 免疫原

      KLH conjugated synthetic peptide derived from human 5-HTR1A:301-400/422 <Cytoplasmic>

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    5HT1A Receptor 5-羟色胺受体1A抗体
    英文名称 5HT1A Receptor
    中文名称 5-羟色胺受体1A抗体
    别    名 5HT1A Receptor; HTR1A; 5-HTR1A; 5 HT 1A; 5 HT receptor 1A; 5 HT1A; 5 HT1A receptor; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled; 5 hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; 5-hydroxytryptamine receptor 1A; 5HT 1A; 5HT 1A receptor; 5HT receptor 1A; 5HT1a; 5HT1A_HUMAN; ADRB2RL1; ADRBRL1; G 21; G protein coupled receptor; G-21; Gpcr 18; Gpcr18; Guanine nucleotide binding regulatory protein-coupled receptor; PFMCD; Serotonin 1A receptor; Serotonin 5HT1A receptor; Serotonin receptor 1A;  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 肿瘤  免疫学  神经生物学  信号转导  转录调节因子  细胞膜受体  G蛋白偶联受体  G蛋白信号  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 46kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human 5-HTR1A:301-400/422 <Cytoplasmic>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012].

    Function:
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.

    SWISS:
    P19327

    Gene ID:
    3350

    Database links:

    Entrez Gene: 487230 Dog

    Entrez Gene: 3350 Human

    Entrez Gene: 15550 Mouse

    Entrez Gene: 24473 Rat

    Omim: 109760 Human

    SwissProt: Q6XXX9 Dog

    SwissProt: Q0EAB6 Horse

    SwissProt: P08908 Human

    SwissProt: Q64264 Mouse

    SwissProt: P19327 Rat

    Unigene: 247940 Human

    Unigene: 4716 Mouse

    Unigene: 44486 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 产品细节图片1
    Protein: Brain(Mouse) Lysate at 40 ug
    Primary: Rabbit Anti- 5HT1A Receptor (bs-1124R) at 1:300; 
    Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000; 
    Predicted band size:46 kD Observed band size:56 kD
    产品细节图片2
    Protein: HepG2 lyates(hu); 
    Primary: Rabbit Anti- 5HT1A Receptor (bs-1124R) at 1:300; 
    Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000; 
    Predicted band size:46 kD Observed band size:56 kD
    产品细节图片3
    Sample: 
    Jurkat(Human) Cell Lysate at 40 ug
    Primary: Anti-5HT1A Receptor (bs-1124R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 46 kD
    Observed band size: 46 kD

    产品细节图片4
    Tissue/cell: rat brain; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-5HT1A Receptor Polyclonal Antibody, Unconjugated(bs-1124R) 1:400, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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