GLP-1R antibody

价格¥780 - 2200

品牌康朗生物
货号kl-1559R
产地中国/美国/德国
更新日期2025年07月10日

应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
宿主Rabbit
适应物种Human, Mouse, Rat, Dog,

上海康朗生物科技有限公司

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供应商：
上海康朗生物科技有限公司
库存：
大量
目录编号：
kl-1559R
克隆性：
多克隆
抗原来源：
Rabbit
保质期：
12个月
抗体英文名：
GLP-1R antibody
抗体名：
胰高血糖素样肽-1受体/GLP-1受体抗体
宿主：
Rabbit
适应物种：
Human, Mouse, Rat, Dog,
免疫原：
KLH conjugated synthetic peptide derived from human GLP-1R C-terminus:101-200/463 <Extracellular>
亚型：
IgG
形态：
冻干粉或液体
应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
浓度：
1mg/ml
保存条件：
-20 °C
规格：
50ul 100ul 200ul

GLP-1R antibody

中文名称	胰高血糖素样肽-1受体/GLP-1受体抗体
别名	Glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; Glp1r; GLP; glp1r; Glucagon like peptide 1 receptor; RATGL1RCP; Glip;MGC138331; GLP-1-R; GLP1R_HUMAN; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Precursor.
	Specific References (2) \| bs-1559R has been referenced in 2 publications. [IF=5.71] Zhou, Hao, et al. "Exendin-4 protects ADMSCs from apoptosis induced by Hydrogen peroxide through PI3K/Akt-Sfrp2 pathways." Free Radical Biology and Medicine (2014). Rat. PubMed:25452142 [IF=3.06] Nagai, Takuo, et al. "Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice." PLOS ONE 11.8 (2016): e0160993. WB, IHC-P ; Mouse. PubMed:27513960
规格价格	50ul/780元购买 100ul/1380元购买 200ul/2200元购买大包装/询价
说明书	50ul 100ul 200ul
研究领域	免疫学生长因子和激素糖尿病
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	51kDa
细胞定位	细胞浆细胞膜
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GLP-1R C-terminus:101-200/463 <Extracellular>
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: GLP1R is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.It has been suggested that this protein influences the feelings of satiety or hunger, sensation of glucose levels, control of glucagon sensitivity of islets, and non insulin-dependent diabetes mellitus. GLP1R is believed to be expressed in human pancreas,lung, brain, stomach, kidney and heart. ESTs have been isolated from skin and kidney libraries. Function: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: May form homodimers and heterodimers with GIPR. Subcellular Location: Cell membrane; Multi-pass membrane protein. Post-translational modifications: N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. Similarity: Belongs to the G-protein coupled receptor 2 family. SWISS: O35659 Gene ID: 2740 Database links: Entrez Gene: 2740 Human Entrez Gene: 14652 Mouse Entrez Gene: 25051 Rat Omim: 138032 Human SwissProt: P43220 Human SwissProt: O35659 Mouse SwissProt: P32301 Rat Unigene: 389103 Human Unigene: 390969 Mouse Unigene: 11408 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GLP-1R是GLP-1在体内作用的主要靶点,它是一个7次跨膜的G蛋白偶联受体,以cAMP为主要第二信使。GLP-1与GLP-1R结合过程是一个两结构域相互作用的过程,都与胰岛素分泌和糖代谢调节密切相关。
产品图片	Sample: Cerebrum(Rat) Lysate at 40 ug Primary: Anti-GLP-1R (bs-1559R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD Sample: Liver（Mouse） lysate at 30 ug; Primary: Anti- GLP-1R (bs-1559R) at 1:300 dilution; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution; Predicted band size: 51 kD Observed band size: 51 kD Tissue/cell: mouse pancreas tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GLP-1R Polyclonal Antibody, Unconjugated(bs-1559R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GLP-1R Polyclonal Antibody, Unconjugated(bs-1559R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining