This antibody is produced by immunizing mice with recombinant protein corresponding to a region of PCNA.
Gene ID
5111
SwissProt
P12004
Synonyms
PCNA; MGC8367
Category
Cell Cycle / Checkpoint Control
Background
PCNA (Proliferating cell nuclear antigen) is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. It induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities.