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- 详细信息
- 文献和实验
- 技术资料
- 库存:
337
- 英文名:
Recombinant Human Activation B7-1 antigen
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人CD80(B7-1)(国产,进口),我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人CD80(B7-1)(国产,进口)
英文名:Recombinant Human Activation B7-1 antigen
编号:JN1423
规格:10μg|50μg|500μg|1mg
品牌:百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val35-Asn242在C端含有His标签。
CD80/B7-1质量控制:>95%(还原性SDS-PAGE)
CD80/B7-1制剂:冻干品
CD80/B7-1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CD80/B7-1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CD80/B7-1:
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.
我公司的重组人CD80(B7-1)(国产,进口),性价比高,货期短,送货上门,欢迎您来电咨询购买,另外,我公司还生产供应销*(代"售")下列产品:
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重组人CD80(B7-1)(国产,进口)关键词:重组人B7-1,重组CD80,重组人CD80蛋白,JN1423
·重组人IL-12RB1
编号:JN1417
英文名称:Recombinant Human Interleukin-12 receptor subunit beta-1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Cys24-Glu540在C端带有Fc标签。
IL-12RB1质量控制:>95%(还原性SDS-PAGE)
IL-12RB1制剂:冻干品
IL-12RB1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IL-12RB1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IL-12RB1:
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.
重组人CD80(B7-1)(国产,进口)关键词:重组人B7-1,重组CD80,重组人CD80蛋白,JN1423
·重组人血管内皮生长因子C
编号:JN0617
英文名称:Recombinant Human Vascular Endothelial Growth Factor C
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe32-Arg227在C端含有His标签。
proVEGF-C质量控制:>95%(还原性SDS-PAGE)
proVEGF-C制剂:冻干品
proVEGF-C保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
proVEGF-C复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于proVEGF-C:
Vascular Endothelial Growth Factor (VEGF)-C is a member of the VEGF family, a group of polypeptide growth factors which play key roles in the physiology and pathology of many aspects of the cardiovascular system, including vasculogenesis, hematopoiesis, angiogenesis and vascular permeability. While VEGFC is homologous to other members of the VEGF/PDGF family, it contains the C-terminal propeptide which has an unusual structure with tandemly repeated cysteine-rich motifs. Upon biosynthesis, VEGFC is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF signalling in endothelial cells occurs through three tyrosine kinase receptors (VEGFRs) expressed by endothelial cells and hematopoietic precursors, and VEGF-C is a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. It is indicated that VEGFC undergoes a complex proteolytic maturation generating a variety of processed secreted forms with increased activity toward VEGFR-3, but only the fully processed form could activate VEGFR-2. VEGFC may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Knockout of the VEGF-C gene is embryonic lethal late in development, and although cells differentiate into the lymphatic lineage, they fail to sprout and form lymphatic vessels. Inactivation of a single VEGF-C allele results in the development of cutaneous lymphatic hypoplasia and lymphedema.
我公司强烈推荐重组蛋白系列产品,热情期待您的咨询选购重组人CD80(B7-1)(国产,进口)。
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文献和实验CD80 分子 CD80 常用单克隆抗体或代号: B7- 1,BB1 主要表达细胞: Ba,Mac,TStr [B] 分子质量(kDa)和结构: gp60(IgSF) 功 能: 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号 CD80 Aka B7-1, BB1 Ligand for T cell marker CD28 or CTLA4 (CD152
, while the second is provided by the B-cell activation antigens B7-1, or CD80 and B7-2, or CD86 by interaction with the T-cell surface molecules CD28 and CTLA4 Positive staining (normal): interdigitating dendritic cells in T zones of secondary lymphoid organs
200倍稀释(售出前已稀释10倍)。3、 标准品:rHuIFN-α2a(3ng/ml),用时用0.1%BSA-PBS作倍比稀释。4、ABTS底物:ABTS 1mg+0.1M,pH5.0柠檬酸缓冲液 2ml 3% H2O24μl(临用时配)。三、自备试剂和材料1、 进口96孔或国产40孔聚苯乙烯ELISA板(敏感性以进口板稍好)。2、0.1M,pH7.4 PBS配其它液体用。3、 包被缓冲液:0.05M,pH9.6 Na2CO3-NaHCO3缓冲液。 4、 洗涤液:0.05%Tween 20-PBS
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