- $545
- 丹麦BioPorto Diagnostics A/S
- 丹麦
- HYB 333-01
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4-8ºC without exposure to light. No precautions necessary during handling.
- 保质期：
12个月
- 库存：
大量
- 供应商：
上海信裕生物科技有限公司
- 抗体英文名：
Anti-Pertussis Toxin
- 规格：
200ug/1mg
Anti-Pertussis Toxin
- Cat. No.
- HYB 333-01
- Product name
- Anti-Pertussis Toxin
- Description
-
Mouse monoclonal antibody
- Specificity
-
Pertussis toxin. Some reactivity towards the toxoid is also present.
- Immunogen
-
Pertussis toxin
- Application
- ELISA, WB
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
-
IgG1/k
- Clone number
- Vac 020 5D3
- Epitope
-
HYB 333-01 has a different epitope specificity compared to HYB 333-02.
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
Pertussis toxin (islet-activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis, the organism that causes whooping cough.
The purified protein consists of five dissimilar subunits: S1 (MW 28,000), S2 (MW 23,000), S3 (MW 22,000), S4 (MW 11,700) and S5 (MW 9,300), in a molar ratio of 1:1:1:2:1.
The A-protomer, S1 is responsible for the enzymatic activity of the toxin. Together, S2, S3, S4 and S5 comprise the B-oligomer, responsible for binding the toxin to the cell surface.
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文献和实验Bordetella pertussis , the causative agent of whooping cough, secretes a plethora of virulence factors contributing to the onset and characteristic of the disease. The exotoxin pertussis toxin (PT) is regarded as particularly important
百日咳杆菌（ bordetella pertussis ）是人类百日咳的病原菌。百日咳杆菌为卵圆形短小杆菌，大小为 0.5 ～ 1.5 × 0.2 ～ 0.5um ，属鲍特氏菌属 bordetella) ，无鞭毛、芽胞。革兰氏染色阴性。用甲苯胺蓝染色可见两极异染颗粒。专性需氧，初次分离培养时营养要求较高，需用马铃薯血液甘油琼脂培养基（即鲍～金氏培养基）才能生长。经 37 ℃ 2 ～ 3 天培养后，可见细小、圆形、光滑、凸起、银灰色、不透明的菌落，周围有模糊的溶血
一般把来自生物体的高度毒性物质，称为毒素。但是这种概念很不明确，而通常主要是限于高分子物质，进入恒温动物血液后显有毒者，且具有抗原性者。如各种植物毒素（ phytotoxin）及蛇毒和蝎、蜘蛛、蜂毒等动物毒素（ zootoxin）（动物毒腺分泌的毒液一般称为腺毒）。有些非高分子物质，在化学上未阐明以前，有时亦称为毒素，以至后来仍保留其名称，例如河豚毒、霉菌毒等。 toxin（毒素）的语源是希腊语系的 toxicon， toxon（箭）的 toxi－ cos认为可能指的是箭毒
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