- ¥545
- BioPorto
- 丹麦
- HYB 123-05
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20ºC
- 保质期：
1年
- 库存：
30
- 供应商：
上海泽叶生物科技有限公司
- 抗体英文名：
Anti-Corynebacterium diphtheriae toxoid (Diphtheria toxoid)
- 规格：
200ug
Anti-Corynebacterium diphtheriae toxoid (Diphtheria toxoid)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- HYB 123-05
- Product name
- Anti-Corynebacterium diphtheriae toxoid (Diphtheria toxoid)
- Description
- Mouse monoclonal antibody
- Specificity
- HYB 123-05 reacts with diphtheria toxoid and toxin (1).
- Immunogen
- Diphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation.
- Application
- ELISA
- Species reactivity (positive)
- Corynebacterium diphtheriae
- Species reactivity (negative)
- Not determined
- Subclass
- IgG1/k
- Clone number
- 17.6
- Epitope
- Not determined
- Content
- Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
- Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action.
- Application 1
-
ELISA
HYB 123-05 reacts strongly with diphtheria toxoid. HYB 123-05 detects diphtheria toxoid in sandwich ELISA in combination with a polyclonal antibody against the toxoid as capture antibody (1). Strong reaction is also seen in ELISA with diphtheria toxoid coated directly onto the microtiter well.
An antibody pair consisting of HYB 123-09 and HYB 123-05 can be used in a sandwich ELISA when using HYB 123-09 as a coat and biotinylated HYB 123-05 a detection antibody (1).
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