- ¥410
- BioPorto
- 丹麦
- ABS 013-32
- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20ºC
- 保质期：
1年
- 库存：
30
- 供应商：
上海泽叶生物科技有限公司
- 抗体英文名：
Anti-Hemopexin
- 规格：
200ug
Anti-Hemopexin
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- ABS 013-32
- Product name
- Anti-Hemopexin
- Description
-
Mouse monoclonal antibody
- Specificity
-
ABS 013-32 is specific for human hemopexin.
- Immunogen
-
Hemopexin purified from human plasma
- Application
- ELISA
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
-
IgG1/k
- Gene ID
- 3263
- Clone number
- 32
- Epitope
-
Epitope of ABS 013-32 differs from ABS 013-04
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
Hemopexin is a serum glycoprotein that binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Structurally hemopexin consists of two similar halves of approximately 200 amino acid residues connected by a histidine-rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues.
- Application 1
-
ELISA
ABS 013-32 binds hemopexin when coated on ELISA wells.
ABS 013-32 (biotunylated) works as a detecton antibody in sandwich ELISA when coating with ABS 013-04.
The calibration curve of a sandwich assay for Hemopexin using ABS 013-32 as capture antibody and ABS 013-04B as the biotinylated detection antibody.
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文献和实验血红素结合蛋白（hemopexin,Hpx）分子量5.7万，单链多肽，含糖量约22%。正常血浆中含量为500-1000μg/L，和游离血红素有特异结合能力。它可配合结合珠蛋白对血红蛋白进行处理。当广泛溶血时，血浆结合珠蛋白耗竭，循环中游离的血红蛋白可降解为珠蛋白和血红素两部分。血红素不溶于水，可与Hpx结合成复合物而运输到肝，分子中的铁可被机体重新利用，卟啉环降解为胆红素而由胆管排出。Hpx并不能与血红蛋白结合，仅可与血红素可逆地结合，而在血循环中反复利用，这是机体有效地保
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