- ￥3000 - 3999
- Abbiotec
- 美国
- 250838
- 2025年07月16日
- E, WB, IHC
- Mouse
- H, M, R
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PSEN1.
- 亚型：
Mouse Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 宿主：
Mouse
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
Presenilin-1 (C-term)
- 抗体英文名：
Presenilin-1 (C-term) Antibody
- 抗体名：
Presenilin-1 (C-term) Antibody
- 规格：
0.1 mg
Presenilin-1 (C-term) Antibody产品详细介绍：
| 产品名称： | Presenilin-1 (C-term) Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/presenilin-1-c-term-antibody【参考图片】 |
| 货号： | 250838 |
| 规格： | 0.1 mg |
| 产品描述： | Presenilin-1 (PSEN1) is the catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins. Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 and PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Presenilins are also involved in the cleavage of the Notch receptor, either by regulating gamma-secretase activity or by direct proteolytic activity. Three alternative splice variants of PSEN1 have been identified. Defects in PSEN1 are a cause of familial early-onset Alzheimer disease type 3, the most severe form of the disease. |
| 克隆类型： | Mouse Polyclonal Antibody |
| 亚型： | Mouse Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PSEN1. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别名： | Presenilin-1; Protein S182; Presenilin-1 NTF subunit; Presenilin CTF subunit; PSEN1; AD3; PS1; PSNL1 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验于研究。 性能参数 LIST OF ANTBODY PRODUCTS AP8401a BDP1 N-term Antibody AP8408b MEG2 C-term Antibody AP8451b PPP3CA C-term Antibody AP8449b CTDSP1 C-term Antibody AP8408a MEG2 N-term Antibody AP8451a PPP3CA N-term Antibody AP8449
【资源】全面归类网址：毕赤酵母表达各种来源蛋白（细菌，真菌，植物，人类等）
europaea (olive tree) aeroallergen Ole e 1S, 60 mg/L, α-MF[115, 334, 391]Olea europaea 1,3-β-glucanase Ole e 9 C-term.seg.S, 100 mg/L, α-MF, active486Oleaceae sp. (lilac and privet) pollen allergensS, 30 mg/L, reactive481Pepper endo-b-1,4-glucanase cCel1S
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