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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified human complement C1 inhibitor protein
- 亚型:
mouse IgG1
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
单克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
H
- 宿主:
Mouse
- 应用范围:
E
- 浓度:
见详细说明信息
- 靶点:
C1 Inhibitor
- 抗体英文名:
C1 Inhibitor Antibody
- 抗体名:
C1 Inhibitor抗体
- 规格:
0.1 mg
C1 Inhibitor Antibody产品详细介绍:
| 产品名称: | C1 Inhibitor Antibody |
| 说明书: | http://www.abbiotec.com/antibodies/c1-inhibitor-antibody【参考图片】 |
| 货号: | 250122 |
| 规格: | 0.1 mg |
| 产品描述: | The complement C1 inhibitor controls the activation of the C1 complex by forming a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. This process regulates important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Deficiencies in C1 inhibitor cause hereditary angiodema (HAE/HANE), a disorder characterized by episodic local subcutaneous edema and submucosal edema involving the upper respiratory and gastrointestinal tracts. This antibody recognizes human complement C1 inhibitor by ELISA. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | mouse IgG1 |
| 免疫原: | Purified human complement C1 inhibitor protein |
| 适用物种: | H |
| 应用范围: | E |
| 应用说明: | E: 5 mg/ml |
| 别名: | Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; SERPING1; C1IN; C1NH |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验C1 Inhibitor: Quantification and Purification
C1 inhibitor is a multipotent serpin capable of inhibiting the classical and the lectin pathways of complement, the fibrinolytic system, and contact/kinin system of coagulation. Deficiency of C1 inhibitor manifest as hereditary angioedema
C1-Inhibitor: Antigenic and Functional Analysis
The classical pathway of complement is activated in various diseases. A main inhibitor of this pathway is the serpin C1-inhibitor (C1-Inh), which regulates activation at the level of C1. C1-Inh also inhibits the mannan binding lectin (MBL
补体成分 C1(C1q/C1r/C1s) 补体成分:C1q 血清浓度(μg/ml):75 分子量(kDa):410 亚单位(链)及分子量(kDa):A:24各6条B:23各6条C:22各6条 生物学活性:识别IgG、IgMFc的补体结合点 补体成分:C1r 血清浓度(μg/ml):50 分子量(kDa):85
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