H89 dihydrochloride

概述

• 产品名称
  H89 dihydrochloride
• 描述
  Kinase inhibitor
• 生物学描述
  Kinase inhibitor, commonly used as a protein kinase A inhibitor (IC₅₀ = 135 nM). Also inhibits other kinases, including MSK1 , S6K1 and ROCKII (IC₅₀values are 120, 80 and 270 nM, respectively).
• 纯度
  > 98%

性能

• 化学名称
  N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride
• 分子量
  519.28
• 化学结构
  
• 分子式
  C₂₀H₂₀BrN₃O₂S.2HCl
• CAS编号
  130964-39-5
• PubChem识别号
  5702541
• 存放说明
  Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in DMSO to 100 mM and in water to 25 mM (with heating)
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br.Cl.Cl
• 来源

  Synthetic