- ￥1660 - 10760
- Sino Biological
- 北京
- 50503-M02H
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
在-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Mouse CTLA4 / CD152 Protein (ECD, Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
100 µg/1 mg
| 规格： | 100 µg | 产品价格： | ￥1660.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥10760.0 |
小鼠 CTLA-4蛋白|CTLA-4 protein|CTLA-4(Mouse, C-human IgG1-Fc)（产品说明）
蛋白名称：CTLA-4蛋白, CTLA-4 protein
蛋白构建：A DNA sequence encoding the extracellular domain of mouse CTLA4 (NP_033973.2) (Met 1-Phe 162) was fused with the Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.05-0.3μg/mL when stimulated with 1 μg/mL Recombinant Human B7-1/CD80.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Glu 36
蛋白分子量：The secreted recombinant mouse CTLA4/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 368 amino acids and has a predicted molecular mass of 41 kDa. As a result of glycosylation, the apparent molecular mass of rm CTLA4/Fc monomer is approximately 55 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：NP_033973.2
蛋白氨基酸序列：Met1-Phe162
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：CTLA-4蛋白, CTLA-4 protein
蛋白构建：A DNA sequence encoding the extracellular domain of mouse CTLA4 (NP_033973.2) (Met 1-Phe 162) was fused with the Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.05-0.3μg/mL when stimulated with 1 μg/mL Recombinant Human B7-1/CD80.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Glu 36
蛋白分子量：The secreted recombinant mouse CTLA4/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 368 amino acids and has a predicted molecular mass of 41 kDa. As a result of glycosylation, the apparent molecular mass of rm CTLA4/Fc monomer is approximately 55 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：NP_033973.2
蛋白氨基酸序列：Met1-Phe162
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Liu, CH; et al. Combinatorial leaky probiotic for anticancer immunopotentiation and tumor eradication. Cell reports. Medicine, PMID: 39442515
2, Liu, X; et al. Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy. Nature biomedical engineering, PMID: 40670719
2, Liu, X; et al. Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy. Nature biomedical engineering, PMID: 40670719
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重组小鼠 CTLA4 / CD152 蛋白 (ECD, Fc标签)
￥1660 - 10760
