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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human MMP-2 / CLG4A Protein
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/10.00 µg/20.00 µg/50.00 µg/100.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥33640.0 |
|---|---|---|---|
| 规格: | 10.00 µg | 产品价格: | ¥1400.0 |
| 规格: | 20.00 µg | 产品价格: | ¥1920.0 |
| 规格: | 50.00 µg | 产品价格: | ¥5170.0 |
| 规格: | 100.00 µg | 产品价格: | ¥5170.0 |
蛋白名称:MMP-2蛋白, MMP-2 protein
蛋白构建:A DNA sequence encoding the native human MMP2 (NP_004521.1) (Met 1-Cys 660) was expressed and purified.
表达宿主:HEK293 Cells
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:1. Measured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2 (AnaSpec, Catalog # 27076). The specific activity is > 1,000 pmoles/min/µg. 2. Measured by its binding ability in a functional ELISA. 3. Immobilized human MMP2 at 10 μg/mL (100 μl/well) can bind human TIMP2/Fc (Cat: 10396-H01H). The EC50 of human TIMP2/Fc is 0.02 μg/mL. (Activation description: The proenzyme needs to be activated by APMA for an activated form)
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ala 30
蛋白分子量:The recombinant human MMP2 consists of 631 amino acids and migrates as an 72 kDa band as predicted in SDS-PAGE under reducing conditions.
蛋白NP号:NP_004521.1
蛋白氨基酸序列:Met1-Cys660
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 内容
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文献和实验2, Ji, Y; et al. An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity. Pharmacological research, PMID: 36893823
3, Goudy, OJ; et al. In silico evolution of autoinhibitory domains for a PD-L1 antagonist using deep learning models. Proceedings of the National Academy of Sciences of the United States of America, PMID: 38032933
4, McCue, AC; et al. Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy. mAbs, PMID: 38962811
5, Liao, JM; et al. Integrating molecular dynamics simulation with small- and wide-angle X-ray scattering to unravel the flexibility, antigen-blocking, and protease-restoring functions in a hindrance-based pro-antibody. Protein science : a publication of the Protein Society, PMID: 39145427
6, Liu, Q; et al. A matrix metalloproteinase-responsive hydrogel system controls angiogenic peptide release for repair of cerebral ischemia/reperfusion injury. Neural regeneration research, PMID: 38819063
7, Shi, W; et al. A tumor-conditional IL-15 safely synergizes with immunotherapy to enhance antitumor immune responses. Molecular therapy : the journal of the American Society of Gene Therapy, PMID: 39489922
8, Liao, TY; et al. Development of a tumor-region-selective activation monoclonal antibody targeting the 4-1BB receptor for enhanced therapeutic efficacy and safety. International journal of biological macromolecules, PMID: 39978521
9, Zhang, L; et al. Antigen-Targeting Inserted Nanomicelles Guide Pre-Existing Immunity to Kill Head and Neck Cancer. Advanced science (Weinheim, Baden-Wurttemberg, Germany), PMID: 40091501
10, Wang, H; et al. Probiotic-mediated tumor microenvironment reprogramming with protease-sensitive interleukin-15 and photothermal therapy. Cell reports. Medicine, PMID: 40532661
11, Song, L; et al. Universal Fab-Fc masked cytokine prodrug platform: αPD-L1/IL-15 prodrug activates CD44+ CD8+ T cells in tumor-draining lymph nodes to enhance antitumor immunity. Journal for immunotherapy of cancer, PMID: 40744663
flower1946 菜鸟求助各位大虾,要做miRNA的实验,现已知可以查某个特定miRNA的有哪几个调节靶点,那反过来,如果要查调节某个特定蛋白(如MMP-7)的miRNA,该如何查呢?谢谢! zhujoker 可以使用targscan等软件啊,其实现在很多网站都有了,包括sigma也有一些预测 flower1946 感谢楼上 295546
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人基质金属蛋白酶-3(MMP-3)酶联免疫分析(ELISA)
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