bs-10888P

bs-10888P

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  • 2025年10月15日
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      100ug/500ug/20ug

    规格:100ug产品价格:¥1880.0
    规格:500ug产品价格:¥5680.0
    规格:20ug产品价格:¥580.0
    产品编号bs-10888P
    英文名称Recombinant human Leptin, C-His
    中文名称重组人瘦素蛋白
    英文别名LEP; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; OB; Obese Protein; Obesity; Obesity factor; Obesity homolog mouse; Obesity Murine Homolog Leptin; OBS; LEP_human; Recombinant human Leptin, C-His
    性状Lyophilized or Liqui
    纯化方法AC
    理论分子量16
    实际分子量13 kDa
    浓度>0.5 mg/ml
    储存液20mM Tris-HCl (pH8.0) with 8M Urea.
    研究领域

    Cardiovascular > Atherosclerosis > Diabetes associated

    Metabolism > Types of disease > Cancer

    Metabolism > Types of disease > Heart disease

    Metabolism > Types of disease > Obesity

    Neuroscience > Neurology process > Metabolism

    Signal Transduction > Growth Factors/Hormones > Hormones

    Stem Cells > Mesenchymal Stem Cells > Adipogenesis

    亚基Interacts with SIGLEC6.
    亚细胞定位Secreted.
    相似性Belongs to the leptin family.
    功能May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Leptin, the product of the ob (obese) gene, is a 16kD protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function.

     

     

    bs-10888P
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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