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| 规格: | 100ug | 产品价格: | ¥1880.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥5680.0 |
| 规格: | 20ug | 产品价格: | ¥580.0 |
| 产品编号 | bs-10888P |
| 英文名称 | Recombinant human Leptin, C-His |
| 中文名称 | 重组人瘦素蛋白 |
| 英文别名 | LEP; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; OB; Obese Protein; Obesity; Obesity factor; Obesity homolog mouse; Obesity Murine Homolog Leptin; OBS; LEP_human; Recombinant human Leptin, C-His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 16 |
| 实际分子量 | 13 kDa |
| 浓度 | >0.5 mg/ml |
| 储存液 | 20mM Tris-HCl (pH8.0) with 8M Urea. |
| 研究领域 | Cardiovascular > Atherosclerosis > Diabetes associated Metabolism > Types of disease > Cancer Metabolism > Types of disease > Heart disease Metabolism > Types of disease > Obesity Neuroscience > Neurology process > Metabolism Signal Transduction > Growth Factors/Hormones > Hormones Stem Cells > Mesenchymal Stem Cells > Adipogenesis |
| 亚基 | Interacts with SIGLEC6. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the leptin family. |
| 功能 | May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Leptin, the product of the ob (obese) gene, is a 16kD protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function. |

The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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bs-10888P
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