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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Chironex fleckeri Toxin CfTX-1
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Chironex fleckeri Toxin CfTX-1品名简称:
Recombinant Chironex fleckeri Toxin CfTX-1 protein货号:
CSB-EP417651CWM规格:
20μg价格:
2328LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
N/AUniprot No.:
A7L035别名:
Toxin CfTX-1; Toxin 1种属:
Chironex fleckeri (Box jellyfish)蛋白长度:
Full Length of Mature Protein来源:
E.coli分子量:
65.1 kDa表达区域:
21-456aa氨基酸序列:
ESTISSGLNSLKTKIDAKMPSGKQLFDKVVEMQKQIDAKFSNDDERAKVMGAIGSLSTAVGKFQSGDPAKIASGCLDILVGISSVLKDFAKFSPIFSILSLVVGLFSGTKAEESVGSVVKKAVQEQSDQELQEALYGVKREYAVSKAFLDGVRNETSDLSPTEVSALAANVPIYQGVRFIAMVVQRIKYIKPKTESEIKRMLTMLELFTDLCSLRDLILLDLYQLVATPGHSPNIASGIKEVSNLGREEYKKVFEDLLKNDDKETYLFLSYLYPREKNEQSRKIFNFFDLMKVKYDDRLKQDLTGVKIFSNVHWPNYFMCSSNDYLALICTKPYGSLKLDKLNDGYYSIKTTQHDPKICHRYGNYILFTHKRNDDLEKFNFVPVKLEKREIYLLSSKESPNKFAYVPQNADGALFFVDGIPSKVGYGNQGYFTLVE蛋白标签:
N-terminal 6xHis-SUMO-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Has potent hemolytic activity. Is lethal to crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells功能2:
Has potent hemolytic activity. Is lethal to crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells (By similarity).文献:
"Identification, cloning and sequencing of two major venom proteins from the box jellyfish, Chironex fleckeri." Brinkman D., Burnell J. Toxicon 50:850-860(2007)研究领域:
Others请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验一般把来自生物体的高度毒性物质,称为毒素。但是这种概念很不明确,而通常主要是限于高分子物质,进入恒温动物血液后显有毒者,且具有抗原性者。如各种植物毒素( phytotoxin)及蛇毒和蝎、蜘蛛、蜂毒等动物毒素( zootoxin)(动物毒腺分泌的毒液一般称为腺毒)。有些非高分子物质,在化学上未阐明以前,有时亦称为毒素,以至后来仍保留其名称,例如河豚毒、霉菌毒等。 toxin(毒素)的语源是希腊语系的 toxicon, toxon(箭)的 toxi- cos认为可能指的是箭毒
指细菌产生的毒素。可以区分为两种:放到菌体外的称为菌体外毒素( exotoxin);含在体内的,在菌体破坏后而放出的,称为菌体内毒素( endoto- xin)。但是在菌体外毒素中,也有通过菌体的破坏而放出体外的,所以这种区分法并不是很严密的。菌体外毒素大多是蛋白质,其中有的起着酶的作用。白喉杆菌、破伤风杆菌、肉毒杆菌等的毒素均为菌体外毒素。而菌体内毒素,其化学主体是来自细菌细胞壁的脂多糖和蛋白质的复合体,赤痢杆菌、霍乱弧菌及绿脓杆菌等的毒素都是这方面的例子。
霍乱菌产生的外毒素,已经证明它是能引起腹泻的毒素。也称为霍乱肠毒素(cholera enteroto- xin)或霍乱原( choleragen)。可从霍乱菌培养液的上清液提纯的结晶,为分子量约 8万 4千的简单蛋白质,由分子量约 2万 8千的 A亚单位 1分子和分子量约 1万 1千的 B亚单位 5分子所构成。 A亚单位为起表达作用的活性分子,更可分为 A1 及 A2 二部分, A1 为活性部分。其作用机理是由于使腺苷酸环化酶的调控分子( G蛋白) ADP核糖基化,从而失掉三磷酸鸟
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