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UTF1 Rabbit pAb(bs-12207R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-12207R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-12207R
    英文名称UTF1 Rabbit pAb
    中文名称未分化胚胎干细胞转录因子1抗体
    英文别名hUTF 1; hUTF1; Undifferentiated embryonic cell transcription factor 1; UTF 1; UTF1_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Cow)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from Human UTF1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量36 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Developmental Biology > Embryogenesis > Embryonic stem cells > Surface molecules

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Stem Cells > Embryonic Stem Cells > Intracellular

    亚基Binds to the N-terminal region of ATF2. Associates with the TFIID complex through interaction with TBP.
    亚细胞定位Nucleus.
    翻译后修饰Phosphorylated.
    功能Acts as a transcriptional coactivator of ATF2.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64% homology with its mouse counterpart, suggesting a similar role between species. The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    K562(Human) Cell Lysate at 30 ug
    293T(Human) Cell Lysate at 30 ug
    Primary: Anti- UTF1 (bs-12207R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 36 kD
    Observed band size: 36 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 4.8 }}] {Jie Su. et al. Study of spermatogenic and Sertoli cells in the Hu sheep testes at different developmental stages. FASEB J. 2023 Jul;37(8):e23084} {IF} {Sheep}

    [IF={{ 1.6 }}] {Ali Tugrul Akin. et al. Effects of adriamycin on cell differentiation and proliferation in rat testis. BIOTECH HISTOCHEM. 2023 Sep 01} {IHC} {Rat}

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    文献支持
    UTF1 Rabbit pAb(bs-12207R)-50ul/100ul/200ul
    ¥1180 - 2800