Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human Raji cell lysates
Lane 3: Human Jurkat cell lysates
Lane 4: Human HL-60 cell lysates
Primary: Anti-SERCA3 (bs-19653R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 114 kDa
Observed band size: 110 kDa
- ￥1180 - 2800
- Bioss
- bs-19653R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-19653R |
| 英文名称 | SERCA3 Rabbit pAb |
| 中文名称 | 肌浆/内质网钙ATP酶3抗体 |
| 英文别名 | Adenosine triphosphatase calcium; AT2A3_HUMAN; Atp2a3; ATPase Ca(2+) transporting ubiquitous; ATPase Ca++transporting ubiquitous; Calcium pump 3; Calcium translocating P type ATPase; Sarco/endoplasmic reticulum Ca2+ATPase; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA 3; SERCA3; SERCA3b; SR Ca(2+) ATPase 3; SR Ca(2+)-ATPase 3. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Chicken, Cow, Xenopus laevis, Xenopus tropicalis) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SERCA3 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 114 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Metabolism > Plasma Membrane > ATPases Signal Transduction > Signaling Pathway > Calcium Signaling |
| 亚细胞定位 | Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane. |
| 组织特异性 | Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. |
| 相似性 | Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. |
| 功能 | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验相关实验
Measurement of Ca2+-ATPase Activity (in PMCA and SERCA1)
Ca2+ -ATP pumps (those on the plasma membrane; PMCA and sarcoplasmic reticulum; SERCA1) have an important role to play in the regulation of intracellular calcium concentrations. In this chapter, three preparations, two membranes
Heterologous SERCA1a Ca2+ -ATPase (sarco-endoplasmic reticulum Ca2+ -adenosine triphosphatase isoform 1a) from rabbit was expressed in yeast Saccharomyces cerevisiae as a fusion protein, with a biotin acceptor domain (BAD) linked to the SERCA
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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SERCA3 Rabbit pAb(bs-19653R)-50ul/100ul/200ul
￥1180 - 2800
