ZMYND11 | BS69 Rabbit pAb(bs-7697R)-50ul/100ul/200ul产品图

ZMYND11 | BS69 Rabbit pAb(bs-7

697R)-50ul/100ul/200ul
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  • bs-7697R
  • 2026年10月14日
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    北京博奥森生物技术有限公司
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-7697R
    英文名称BS69 Rabbit pAb
    中文名称腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1抗体
    英文别名Adenovirus 5 E1A binding protein; Bone morphogenetic protein receptor associated molecule 1; BRAM1; BS69 variant 1; BS69 variant 2; BS69 variant 3; BS69 variant 4; Zinc finger MYND domain containing 11; ZMYND11.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Chicken, Dog, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ZMYND11/BS69
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量71 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell Cycle Inhibitors

    Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription

    Epigenetics and Nuclear Signaling > Transcription > RNA polymerase

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    Immunology > Immune System Diseases > Antiviral Signaling

    亚基 Interacts (via MYND-type zinc finger) with NCOR1. Interacts (via MYND-type zinc finger) with human adenovirus early E1A protein (via PXLXP motif); this interaction inhibits E1A mediated transactivation. Interacts (via MYND-type zinc finger) with Epstein-Barr virus EBNA2 protein (via PXLXP motif). Interacts (via MYND-type zinc finger) with EZH2. Interacts with E2F6.
    亚细胞定位Nucleus. Chromosome. Note=Associates with chromatin and mitotic chromosomes.
    组织特异性Ubiquitous.
    翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    Ubiquitinated, leading to proteasomal degradation. _x000D_
    相似性Contains 1 bromo domain._x000D_
    Contains 1 MYND-type zinc finger._x000D_
    Contains 1 PHD-type zinc finger._x000D_
    Contains 1 PWWP domain._x000D_
    功能Corepressor of transcription (Probable). May be involved in chromatin remodeling through association with several remodeling factors.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: rat brain tissue; 4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    _x000D_ Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    _x000D_ Incubation: Anti-BS69/Adenovirus 5 E1A binding protein Polyclonal Antibody, Unconjugated (bs-7697R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
    _x000D_

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    图标文献和实验
    该产品被引用文献
    [1]Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles
    PMID:34023506Mol Ther2021-10-06
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    ZMYND11 | BS69 Rabbit pAb(bs-7697R)-50ul/100ul/200ul
    ￥1180 - 2800