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- bs-9599R
- 2025年10月16日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-9599R |
| 英文名称 | TAS1R2 Rabbit pAb |
| 中文名称 | G蛋白偶联受体71抗体 |
| 英文别名 | TS1R2_HUMAN; Taste receptor type 1 member 2; G-protein coupled receptor 71; Sweet taste receptor T1R2; TR2; T1R2; GPR71; GPCR TAS1R2; |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Cow) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GPR71/T1R2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 95 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Sensory System > Taste system Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell Membrane: Multi-pass membrane protein |
| 相似性 | Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. |
| 功能 | GPCR TAS1R2 is a putative taste receptor. It recognizes diverse natural and synthetic sweeteners. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Contributes to sweet taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of sweet taste and positive regulation of cytokinesis. Part of sweet taste receptor complex. [provided by Alliance of Genome Resources, Apr 2022] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 6.7 }}] {Yu Shanjun. et al. Extendin-4 blockade of T1R2/T1R3 activation improves Pseudomonas aeruginosa-related pneumonia in an animal model of chemically induced diabetes. INFLAMM RES. 2024 May;:1-17} {IF} {Rat,Human}
[IF={{ 4.8 }}] {Shanjun Yu. et al.Exendin-4 blockade of T1R2/T1R3 activation improves Pseudomonas aeruginosa-related pneumonia in an animal model of chemically induced diabetes.Inflammation Research.2024 Jul;73(7):1185-1201.} {IF} {Human, Rat}
[IF={{ 4.8 }}] {Zhen-Ran Hu. et al. BuZhong YiQi Formula Alleviates Taste Disorders in Rats with Type 2 Diabetes Mellitus by Increasing the Number of Taste Buds and the Expression of Signaling Molecules in Taste Transduction Pathways. PHARMACEUTICALS-BASE. 2025 Jun;18(6):838} {IF,WB} {Rat}
[IF={{ 2.614 }}] {Kang C et al. L‐glutamate stimulates cholecystokinin secretion via the T1R1/T1R3 mediated PLC/TRPM5 transduction pathway. J Sci Food Agric . 2020 Oct;100(13):4818-4825.} {WB} {Rat}
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