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Cytokeratin 13 Rabbit pAb(bs-1

717R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1717R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1717R
    英文名称Cytokeratin 13 Rabbit pAb
    中文名称细胞角蛋白13抗体
    英文别名type I cytoskeletal 13; 47 kDa cytokeratin; CK-13; CK13; Cytokeratin-13; K13; K1C13_HUMAN; Ka13; Keratin 13; Keratin; keratin type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; MGC161462; MGC3781; Type I keratin Ka13; Keratin, type I cytoskeletal 13; K13.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Dog, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Cytokeratin-13
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量49 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class I > Cytokeratins

    Tags & Cell Markers > Cell Type Markers > Epi / Endo-thelial

    亚基Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.
    组织特异性Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) . WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
    相似性Belongs to the intermediate filament family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Lane 1: Mouse Uterus tissue lysates
    Lane 2: Mouse Urinary bladder tissue lysates
    Lane 3: Mouse Ear tissue lysates
    Primary: Anti-Cytokeratin 13 (bs-1717R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49 kDa
    Observed band size: 49 kDa

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    该产品被引用文献

    [IF={{ 3.061 }}] {Chen YT et al. Extracorporeal shock wave markedly alleviates radiation-induced chronic cystitis in rat.Am J Transl Res. 2018 Mar 15;10(3):1036-1052.} {IHC} {Rat}

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    文献支持
    Cytokeratin 13 Rabbit pAb(bs-1717R)-50ul/100ul/200ul
    ¥1180 - 2800