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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-7524R |
| 英文名称 | Thrombospondin 2 Rabbit pAb |
| 中文名称 | 血小板反应蛋白2/凝血酶敏感蛋白2抗体 |
| 英文别名 | THBS2; Thrombospondin-2; Thrombospondin2; TSP2; TSP2_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Thrombospondin 2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 128 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic inhibitory factors Cardiovascular > Angiogenesis > Inhibitors |
| 亚基 | Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin and type V collagen. |
| 组织特异性 | High expression in invertebral disk tissue. |
| 相似性 | Belongs to the thrombospondin family. Contains 2 EGF-like domains. Contains 1 laminin G-like domain. Contains 1 TSP C-terminal (TSPC) domain. Contains 3 TSP type-1 domains. Contains 8 TSP type-3 repeats. Contains 1 VWFC domain. |
| 功能 | Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

HUVEC(Human) Cell Lysate at 40 ug
Primary: Anti-Thrombospondin 2 (bs-7524R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 128 kD
Observed band size: 128 kD

MG63(Human) Cell Lysate at 40 ug
Primary: Anti-Thrombospondin 2 (bs-7524R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 128 kD
Observed band size: 128 kD
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文献和实验[IF={{ 4.638 }}] {Li Jianxiong. et al. Whole-exome mutational landscape and molecular marker study in mucinous and clear cell ovarian cancer cell lines 3AO and ES2. BMC CANCER. 2023 Dec;23(1):1-13} {WB,IF} {Human}
[IF={{ 2.22 }}] {Ken-Go Hayashi. et al. Differential expression of pro- and anti-angiogenic factors in the endometrium between repeat breeder and normally fertile cows. ANIM REPROD SCI. 2023 Jul;254:107265} {IHC} {Bovine}
[IF={{ 1.33 }}] {Chen, Junying, et al. "MiR-1246 promotes SiHa cervical cancer cell proliferation, invasion, and migration through suppression of its target gene thrombospondin 2." Archives of Gynecology and Obstetrics (2014): 1-8.} {WB} {="Human"}
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