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PTGEs/Prostaglandin E Synthase

Rabbit pAb(bs-1880R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1880R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1880R
    英文名称PTGEs/Prostaglandin E Synthase Rabbit pAb
    中文名称前列腺素E合成酶抗体
    英文别名Glutathione S transferase 1 like 1; MGC10317; MGST IV; MGST1 L1; MGST1 like 1; MGST1-L1; MGST1L1; MGSTIV; Microsomal glutathione S transferase 1 like 1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; Microsomal prostaglandin E synthase 1; mPGES 1; MPGES; mPGES-1; p53 induced apoptosis protein 12; p53 induced gene 12; p53 induced gene 12 protein; p53-induced gene 12 protein; PGES; PIG 12; PIG12; PP 102; PP 1294; PP102; PP1294; Prostaglandin E synthase; PTGES; PTGES_HUMAN; TP53I12; Tumor protein p53 inducible protein 12.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PTGEs
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量17 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Immune System Diseases > Autoimmune

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Signal Transduction > Signaling Pathway > Lipid Signaling > Prostaglandins

    亚基Homotrimer.
    亚细胞定位Membrane; Multi-pass membrane protein.
    相似性Belongs to the MAPEG family.
    功能Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Jurkat(Human) Cell Lysate at 30 ug
    Primary: Anti-PTGEs (bs-1880R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 17 kD
    Observed band size: 18 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 5.9 }}] {Yue Song. et al. Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea. FRONT IMMUNOL. 2025 Jun;16:} {WB} {Rat}

    [IF={{ 25.606 }}] {Zhou, Lei. et al. Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation. Nat Immunol. 2022 Jan;23(2):251-261} {FCM} {Human}

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    PTGEs/Prostaglandin E Synthase Rabbit pAb(bs-1880R)-50ul/100ul/200ul
    ¥1180 - 2800