Sample:
Lane 1: Mouse Uterus tissue lysates
Lane 2: Mouse Small intestine tissue lysates
Lane 3: Mouse Kidney tissue lysates
Lane 4: Mouse Prostate tissue lysates
Primary: Anti-EP4 (bs-8538R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 55 kD
- ￥1180 - 2800
- Bioss
- bs-8538R
- 2025年10月16日
- 产品信息以Bioss网站为准
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-8538R |
| 英文名称 | EP4 Rabbit pAb |
| 中文名称 | 前列腺素E受体蛋白4抗体 |
| 英文别名 | Prostaglandin E Receptor EP4; EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER 2; PTGER 4; PTGER2; PTGER4. |
| 产品应用 | WB=1:500-2000, Flow-Cyt=2ug/Test Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse EP4R/Prostaglandin E Receptor EP4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 53 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR Signal Transduction > Signaling Pathway > Lipid Signaling > Prostaglandins |
| 亚基 | Interacts with FEM1A. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. |
| 翻译后修饰 | Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {Flow-Cyt} | {2ug/Test} |
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文献和实验该产品被引用文献
[IF={{ 9.423 }}] {Xi He. et al. Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche. Cell Rep. 2021 Sep;36:109674} {IF} {mouse}
[IF={{ 7.01 }}] {Xin Wang. et al. Irreversible Electroporation Improves Tendon Healing in a Rat Model of Collagenase-Induced Achilles Tendinopathy. AM J SPORT MED. ;():} {IHC,IF} {Rat}
[IF={{ 4.622 }}] {Seung-Yub Song. et al. Purification of phenoloxidase from Haliotis discus hannai and its anti-inflammatory activity in vitro. FISH SHELLFISH IMMUN. 2023 Jun;137:108741} {WB} {Human}
[IF={{ 4.5 }}] {Haojie Chen. et al. Association Between Vertebral Endplate Defects and Patient-reported Symptoms: An Immunohistochemical Study Investigating the COX-2/PGE-2/EP-4 Axis. SPINE J. 2024 Apr;:} {IHC} {Human}
[IF={{ 4.5 }}] {Koyama, Hiroyuki, et al. "Comprehensive Profiling of GPCR Expression in Ghrelin-producing Cells." Endocrinology (2016): en-2016.} {IHC} {="Mouse"}
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EP4 Rabbit pAb(bs-8538R)-50ul/100ul/200ul
￥1180 - 2800
