ABCC5 | MRP5 Rabbit pAb(bs-1437R)-50ul/100ul/200ul产品图
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ABCC5 | MRP5 Rabbit pAb(bs-143

7R)-50ul/100ul/200ul
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  • ￥1180 - 2800
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  • bs-1437R
  • 2026年10月13日
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    北京博奥森生物技术有限公司
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    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-1437R
    英文名称MRP5 Rabbit pAb
    中文名称多药耐药相关蛋白5抗体
    英文别名Multidrug Resistanec-Associated Protein 5; ABC 33; ABC33; ABCC 5; ABCC5; ATP binding cassette sub family C(CFTR/MRP) member 5; ATP binding cassette sub family C member 5; Canalicular multispecific organic anion transporter C; DKFZp686C1782; EST277145; MOAT C; MOATC; MRP 5; Multi specific organic anion tranporter C; pABC 11; pABC11; SMRP; MRP5_HUMAN.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human MRP5
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量160 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Plasma Membrane > ATPases

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Membrane; Multi-pass membrane protein.
    组织特异性All isoforms are equally expressed in retina.
    相似性Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
    功能Acts as a multispecific organic anion pump which can transport nucleotide analogs.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    图标文献和实验
    该产品被引用文献
    [1]PPARγ contributes to cardioprotection against heat stroke through ABCC5-dependent lipid metabolism.
    PMID:41819784Redox Biol2026-05
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    ABCC5 | MRP5 Rabbit pAb(bs-1437R)-50ul/100ul/200ul
    ￥1180 - 2800