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- bs-5884R
- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-5884R |
| 英文名称 | Endomucin Rabbit pAb |
| 中文名称 | 内皮粘蛋白EMCN抗体 |
| 英文别名 | Endomucin 2; Mucin 14; EMCN; EMCN2; Endomucin; Endomucin-2; Endothelial sialomucin; Gastric cancer antigen Ga34; MUC-14; MUCEN_HUMAN; Mucin-14. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Cow) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Endomucin |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 25 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > ECM > Extracellular matrix Cardiovascular > Angiogenesis > Endothelial Cell Markers Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Glucosaminoglycans |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks. Isoform 2: Secreted (Potential). |
| 组织特异性 | Expressed in heart, kidney and lung. |
| 翻译后修饰 | Highly O-glycosylated. Sialic acid-rich glycoprotein. |
| 功能 | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 8.09 }}] {Shinki Koyama. et al. Angio-osteogenic capacity of octacalcium phosphate co-precipitated with copper gluconate in rat calvaria critical-sized defect. Sci Technol Adv Mat. 2022;23(1):120-139} {IHC} {Rat}
[IF={{ 7.1 }}] {Li Juanjuan. et al. Inhibition of soluble epoxide hydrolase reverses bone loss in periodontitis by upregulating EMCN and inhibiting osteoclasts. STEM CELL RES THER. 2024 Dec;15(1):1-14} {IF} {Human}
[IF={{ 28.213 }}] {Xu, Xi. et al. PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia. NAT CELL BIOL. 2023 Jan;:1-13} {ICC} {Mouse}
[IF={{ 2.7 }}] {Yi Zhang. et al. An Optimized Protocol for Multiple Immunohistochemical Staining of Fragile Tissue Samples. Tissue Engineering Part C-Methods. 2024 Dec 02} {mIHC} {Rat}
[IF={{ 16.806 }}] {Jie Mi. et al. Implantable Electrical Stimulation at Dorsal Root Ganglions Accelerates Osteoporotic Fracture Healing via Calcitonin Gene-Related Peptide. 2021 Oct 28} {IHC} {Rat}
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