Sample:
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti-NOD2 (bs-7084R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 114 kD
Observed band size: 114 kD
- ￥1180 - 2800
- Bioss
- bs-7084R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7084R |
| 英文名称 | CARD15/NOD2 Rabbit pAb |
| 中文名称 | 凋亡加强结构域蛋白15抗体 |
| 英文别名 | ACUG; Arthrocutaneouveal granulomatosis; BLAU; CARD15; Caspase recruitment domain protein 15; Caspase recruitment domain-containing protein 15; CD; IBD1; Inflammatory bowel disease protein 1; LRR containing protein; LRR-containing protein; Nod2; NOD2 protein; NOD2_HUMAN; NOD2B; nucleotide binding oligomerization domain 2; nucleotide-binding oligomerization domain 2; Nucleotide-binding oligomerization domain-containing protein 2; PSORAS1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CARD15 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 114 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Caspases etc > CARD Family |
| 亚基 | Binds to RIPK2/RICK by CARD-CARD interaction. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Monocytes-specific. |
| 相似性 | Contains 2 CARD domains.
Contains 9 LRR (leucine-rich) repeats. Contains 1 NACHT domain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
A549(Human) Cell Lysate at 30 ug
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti-NOD2 (bs-7084R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 114 kD
Observed band size: 114 kD
A549(Human) Cell Lysate at 30 ug
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti-NOD2 (bs-7084R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 114 kD
Observed band size: 114 kD
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文献和实验该产品被引用文献
[IF={{ 6.208 }}] {Lan Yang. et al. Lactobacillusjohnsonii L531 Protects against Salmonella Infantis-Induced Intestinal Damage by Regulating the NOD Activation, Endoplasmic Reticulum Stress, and Autophagy. INT J MOL SCI. 2022 Jan;23(18):10395} {WB} {Pig, Human}
[IF={{ 4.7 }}] {Yanjie Li. et al. β-Glucan modulates trained immunity to inhibit osteoclast differentiation via NOD2/RIPK2 signaling pathway. INT IMMUNOPHARMACOL. 2025 Jun;159:114886} {WB} {Mouse}
[IF={{ 3.9 }}] {Jun Yang. et al. A PANoptosis-Based Signature for Survival and Immune Predication in Glioblastoma Multiforme. ANN CLIN TRANSL NEUR. 2025 May;:} {WB} {Human}
[IF={{ 2.9 }}] {David Zapico. et al. A nod to paratuberculosis: NOD1 and NOD2 expression in the pathological spectrum of Mycobacterium avium subsp. paratuberculosis infection in cattle. FRONT VET SCI. 2025 May;12:} {IHC} {Human}
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CARD15/NOD2 Rabbit pAb(bs-7084R)-50ul/100ul/200ul
￥1180 - 2800
