CARD15/NOD2 antibody

CARD15/NOD2 antibody

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  • ¥780 - 2200
  • 康朗生物
  • kl-7084R
  • 中国/美国/德国
  • 2025年11月21日
  • WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1ug/Test
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-7084R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      CARD15/NOD2 antibody

    • 抗体名

      凋亡加强结构域蛋白15抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human CARD15:251-350/1040

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1ug/Test

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    CARD15/NOD2 antibody
    中文名称 凋亡加强结构域蛋白15抗体
    别    名 ACUG; Arthrocutaneouveal granulomatosis; BLAU; CARD15; Caspase recruitment domain protein 15; Caspase recruitment domain-containing protein 15; CD; IBD1; Inflammatory bowel disease protein 1; LRR containing protein; LRR-containing protein; Nod2; NOD2 protein; NOD2_HUMAN; NOD2B; nucleotide binding oligomerization domain 2; nucleotide-binding oligomerization domain 2; Nucleotide-binding oligomerization domain-containing protein 2; PSORAS1.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 细胞生物  免疫学  细胞凋亡  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1ug/Test (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 114kDa
    细胞定位 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CARD15:251-350/1040 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement.

    Subunit:
    Binds to RIPK2/RICK by CARD-CARD interaction.

    Subcellular Location:
    Cytoplasm.

    Tissue Specificity:
    Monocytes-specific.

    Similarity:
    Contains 2 CARD domains. 
    Contains 9 LRR (leucine-rich) repeats. 
    Contains 1 NACHT domain.

    SWISS:
    Q9HC29

    Gene ID:
    64127

    Database links:

    Entrez Gene: 64127 Human

    Entrez Gene: 257632 Mouse

    Entrez Gene: 291912 Rat

    Omim: 605956 Human

    SwissProt: Q9HC29 Human

    SwissProt: Q8K3Z0 Mouse

    Unigene: 592072 Human

    Unigene: 222633 Mouse

    Unigene: 218600 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    CARD15与家族性肠黏膜克罗恩病有关。
    产品图片 CARD15/NOD2 antibody
    Sample: 
    MCF-7(Human) Cell Lysate at 30 ug
    Primary: Anti-NOD2 (bs-7084R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 114 kD
    Observed band size: 114 kD

    CARD15/NOD2 antibody
    Sample: 
    A549(Human) Cell Lysate at 30 ug
    MCF-7(Human) Cell Lysate at 30 ug
    Primary: Anti-NOD2 (bs-7084R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 114 kD
    Observed band size: 114 kD

    CARD15/NOD2 antibody
    Blank control(blue): Raji(fixed with 2% paraformaldehyde (10 min)). 
    Primary Antibody:Rabbit Anti-CARD15/AF488 Conjugated antibody(bs-7084R-/AF488 ), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; 
    Isotype Control Antibody: Rabbit IgG/AF488(orange) ,used under the same conditions );

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