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SFTPC Rabbit pAb(bs-10067R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-10067R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-10067R
    英文名称SFTPC Rabbit pAb
    中文名称肺表面活性蛋白C抗体
    英文别名PSP C; PSPC; Pulmonary surfactant apoprotein 2; pulmonary surfactant apoprotein PSP C; pulmonary surfactant associated protein C; pulmonary surfactant associated proteolipid SPL pVal; Pulmonary surfactant associated proteolipid SPL(Val); SFTP 2; SFTP2; SP-C; SFTPC surfactant pulmonary associated protein C; SP 5; SP C; SP5; SPC; surfactant associated protein pulmonary 2; Surfactant protein c; Surfactant pulmonary associated protein C; PSPC_HUMAN.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Cow, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SFTPC
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量4/21 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
    相似性Contains 1 BRICHOS domain.
    功能Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

    产品细节图片1
    Cell: NCI-H460
    Concentration:1:100
    Host/Isotype:Rabbit/IgG
    Flow cytometric analysis of Rabbit IgG isotype control (Cat#: bs-10067R) on NCI-H460(green) compared with control in the absence of primary antibody (blue) followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG(H+L) secondary antibody .

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    该产品被引用文献

    [IF={{ 5.656 }}] {Kerr NA et al. Human Lung Cell Pyroptosis Following Traumatic Brain Injury. Cells. 2019 Jan 18;8(1). pii: E69.} {FCM} {Human}

    [IF={{ 5.6 }}] {Lei Chen. et al. Luteolin Enhances Transepithelial Sodium Transport in the Lung Alveolar Model: Integrating Network Pharmacology and Mechanism Study. INT J MOL SCI. 2023 Jan;24(12):10122} {IF,FCM} {Mouse}

    [IF={{ 4.01 }}] {Yang et al. CXCR4 receptor overexpression in mesenchymal stem cells facilitates treatment of acute lung injury in rats. (2015) J.Biol.Chem. 290:1994-2006} {Other} {Rat}

    [IF={{ 3.84 }}] {Dinh, Phuong-Uyen C., et al. "Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies." Respiratory Research 18.1 (2017): 132.} {FCM} {="Human"}

    [IF={{ 3.52 }}] {Yan, Wang, et al. "SB203580 inhibits epithelial–mesenchymal transition and pulmonary fibrosis in a rat silicosis model." Toxicology Letters (2016).} {FCM} {="Rat"}

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    文献支持
    SFTPC Rabbit pAb(bs-10067R)-50ul/100ul/200ul
    ¥1180 - 2800