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Nox1 Rabbit pAb(bs-3682R)-50ul

/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-3682R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-3682R
    英文名称Nox1 Rabbit pAb
    中文名称有丝分裂氧化酶1抗体
    英文别名Mitogenic oxidase 1; MOX1; NADH/NADPH mitogenic oxidase subunit P65 MOX; NADPH oxidase 1; NADPH oxidase 1 variant NOH 1L; NADPH oxidase homolog 1; NOH 1; NOH1; RP1-146H21.1; GP91-2; Mitogenic oxidase(pyridine nucleotide dependent superoxide generating).
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat, Dog, Cow, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Nox1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量62 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Other Antibodies > Oxidative Stress

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > DNA Damage Response

    Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism

    Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚基NOX1, NOXA1, NOXO1, RAC1 and CYBA forms a functional multimeric complex supporting ROS production. Interacts with NOXA1 and NOXO1.
    亚细胞定位Cell projection, invadopodium membrane; Multi-pass membrane protein.
    组织特异性NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH-1S is detected only in colon and colon carcinoma cells.
    相似性Contains 1 FAD-binding FR-type domain.
    Contains 1 ferric oxidoreductase domain.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The NOX family NADPH protein oxidases are involved in transfer of electrons accross membranes to generate reactive oxygen species. There are 7 family members - NOX1-5, DUOX1 and DUOX2. Expression of NOX1 is highest in colon tissue; it is also found in vascular tissue and can also been induced by a variety of factors including PDGF. It requires interaction with NOXO1 and NOXA1 for superoxide generation.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample: Testis (Mouse) Lysate at 40 ug
    Primary: Anti- Nox1 (bs-3682R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/10000 dilution
    Predicted band size: 62 kD
    Observed band size: 57 kD
    产品细节图片2
    Sample:
    Testis (Mouse) Lysate at 40 ug
    Uterus (Mouse) Lysate at 40 ug
    DU145(Human) Cell Lysate at 30 ug
    Primary: Anti- Nox1 (bs-3682R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 62 kD
    Observed band size: 60 kD
    产品细节图片3
    Sample:
    Heart (Mouse) Lysate at 40 ug
    Primary: Anti-Nox1 (bs-3682R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 62 kD
    Observed band size: 62 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 9.038 }}] {Xie C et al. Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK. J Hazard Mater . 2020 Jul 15;394:122549.} {WB,IF} {mouse}

    [IF={{ 8.401 }}] {Mr. Aleksandr Vendrov. et al. Renal NOXA1/NOX1 Signaling Regulates Epithelial Sodium Channel and Sodium Retention in Angiotensin II-induced Hypertension. 2021 Oct 29} {IF,IHC} {Mouse}

    [IF={{ 6.1 }}] {Yun, Yang, et al. "Sulfate Aerosols Promote Lung Cancer Metastasis by Epigenetically Regulating the Epithelial-to-Mesenchymal Transition (EMT)." Environmental Science & Technology (2017).} {WB} {="Human"}

    [IF={{ 5.307 }}] {Xu Zhou. et al. Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression. BIOORG CHEM. 2022 Nov;128:106034} {IHC} {Mouse}

    [IF={{ 5.243 }}] {Peng Ding. et al. BMPER alleviates ischemic brain injury by protecting neurons and inhibiting neuroinflammation via Smad3-Akt-Nrf2 pathway. 2021 Dec 14} {WB} {Mouse}

    相关实验
    • Immunochemical Detection of a Fluorophore Derived from the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Lysine

      = NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific

    • 亲和层析凝胶指南

      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

    • 亲和层析凝胶指南

      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

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    文献支持
    Nox1 Rabbit pAb(bs-3682R)-50ul/100ul/200ul
    ¥1180 - 2800