Sample:
_x000D_
placenta (Mouse) Lysate at 40 ug
_x000D_
Primary: Anti-IL22R (Bs-2624R) at 1/300 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 61 kD
_x000D_
Observed band size: 65 kD
- ￥1180 - 2800
- Bioss
- bs-2624R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2624R |
| 英文名称 | IL22R Rabbit pAb |
| 中文名称 | 白介素22受体抗体 |
| 英文别名 | IL-22R; CRF2 9; IL22 Receptor alpha; cytokine receptor classII member 9; cytokine receptor family 2 member 9; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL22R; IL22R1; IL22RA1; ILTIF R1 chain; Interleukin 22 Receptor alpha 1; Interleukin 22 Receptor; Interleukin-22 receptor subunit alpha-1; ZcytoR11; I22R1_HUMAN; IL-22 receptor subunit alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Dog, Pig, Cow, Horse, Rabbit, GuineaPig) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IL-22R |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 61 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interleukins Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Adapters > Transmembrane |
| 亚基 | Heterodimer with IL10RB and with IL20RB. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed in kidney, liver and lung. |
| 相似性 | Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. |
| 功能 | Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
_x000D_ Lane1: Liver(Mouse) Lysate at 30 ug
_x000D_ Lane2: Intestinal(Mouse) Lysate at 30 ug
_x000D_ Primary: Anti-IL22R (bs-2624R) at 1:300 dilution;
_x000D_ Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
_x000D_ Predicted band size : 61kD
_x000D_ Observed band size : 61kD
_x000D_
_x000D_ Lane1: Liver(Mouse) Lysate at 30 ug
_x000D_ Lane2: Intestinal(Mouse) Lysate at 30 ug
_x000D_ Primary: Anti-IL22R (bs-2624R) at 1:300 dilution;
_x000D_ Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
_x000D_ Predicted band size : 61kD
_x000D_ Observed band size : 61kD
_x000D_
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IL22RA1 | IL-22R Rabbit pAb(bs-2624R)-50ul/100ul/200ul
￥1180 - 2800
