IL22R Rabbit pAb(bs-2624R)-50ul/100ul/200ul
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IL22R Rabbit pAb(bs-2624R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-2624R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-2624R
    英文名称IL22R Rabbit pAb
    中文名称白介素22受体抗体
    英文别名IL-22R; CRF2 9; IL22 Receptor alpha; cytokine receptor classII member 9; cytokine receptor family 2 member 9; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL22R; IL22R1; IL22RA1; ILTIF R1 chain; Interleukin 22 Receptor alpha 1; Interleukin 22 Receptor; Interleukin-22 receptor subunit alpha-1; ZcytoR11; I22R1_HUMAN; IL-22 receptor subunit alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat, Dog, Pig, Cow, Horse, Rabbit, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human IL-22R
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量61 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Innate Immunity > Cytokines > Interleukins

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Signal Transduction > Adapters > Transmembrane

    亚基Heterodimer with IL10RB and with IL20RB.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Expressed in kidney, liver and lung.
    相似性Belongs to the type II cytokine receptor family.
    Contains 2 fibronectin type-III domains.
    功能Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    IL22R Rabbit pAb(bs-2624R)-50u
    Sample:
    placenta (Mouse) Lysate at 40 ug
    Primary: Anti-IL22R (Bs-2624R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 61 kD
    Observed band size: 65 kD
    IL22R Rabbit pAb(bs-2624R)-50u
    Sample:
    Lane1: Liver(Mouse) Lysate at 30 ug
    Lane2: Intestinal(Mouse) Lysate at 30 ug
    Primary: Anti-IL22R (bs-2624R) at 1:300 dilution;
    Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
    Predicted band size : 61kD
    Observed band size : 61kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 8.65 }}] {Kulkarni et al. Toll-like receptor 4-induced IL-22 accelerates kidney regeneration. (2014) J.Am.Soc.Nephrol. 25:978-89} {IHC} {Mouse}

    [IF={{ 8.109 }}] {Jane A. Lindborg. et al. Optic nerve regeneration screen identifies multiple genes restricting adult neural repair. Cell Rep. 2021 Mar;34:108777} {IHC} {Mouse}

    [IF={{ 6.208 }}] {Yanan Hao. et al. Alginate Oligosaccharides Repair Liver Injury by Improving Anti-Inflammatory Capacity in a Busulfan-Induced Mouse Model. INT J MOL SCI. 2023 Jan;24(4):3097} {IF} {Mouse}

    [IF={{ 4 }}] {Zhengchen Jiang. et al. IL-22 relieves hepatic ischemia-reperfusion injury by inhibiting mitochondrial apoptosis based on the activation of STAT3. INT J BIOCHEM CELL B. 2024 Jan;166:106503} {IF} {Mouse}

    [IF={{ 3.061 }}] {Wanzhen Li. et al. Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice via regulating IL-22/IL-22R1/STAT3 signaling. PEERJ. 2022 Sep;10:e14086} {WB} {Mouse}

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    文献支持
    IL22R Rabbit pAb(bs-2624R)-50ul/100ul/200ul
    ¥1180 - 2800