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AQP9 Rabbit pAb(bs-2060R)-50ul

/100ul/200ul
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  • ￥1180 - 2800
  • Bioss已认证
  • bs-2060R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-2060R
    英文名称AQP9 Rabbit pAb
    中文名称水通道蛋白-9抗体
    英文别名aquaporin Protein-9; Aquaporin 9; AQP 9; AQP9; Aquaporin9; HsT 17287; HsT17287; Small solute channel 1; SSC 1; SSC1; Aquaporin-9; AQP-9; Aquaglyceroporin-9; AQP9_HUMAN.
    产品应用Flow-Cyt=1μg /test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human AQP9
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量32 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Membrane; Multi-pass membrane protein.
    组织特异性Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.
    相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
    功能Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料牋?Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". A new member of AQP family, Aquaporin-9 (AQP9), has been cloned from human leukocytes by homology cloning (Ishibashi et al. 1997). It is mostly homologous with AQP3 and AQP7 (54-48% identity). AQP9 (295 AA) is primarily expressed in peripheral leukocytes, and lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and AQP7, it did not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. A new member of the AQP family, AQP9, has been cloned from human leukocytes. It is homologous with AQP3 and AQP7 (54-48% identity). AQP9 (295aa) is primarily expressed in peripheral leukocytes, and in lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and AQP7, it does not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic.牋牋Other Aliases:牋?aquaporin Protein -9; AQP 9; AQP9; Aquaporin9; HsT 17287; HsT17287; Small solute channel 1; SSC 1; SSC1.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg /test}

     

    产品细节图片1
    Blank control: A549(blue).
    Primary Antibody: Rabbit Anti- AQP9/AF647 Conjugated antibody (bs-2060R /AF647), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
    Isotype Control Antibody: Rabbit IgG/AF647(orange) ,used under the same conditions.
    Protocol
    The cells were fixed with 2% P‌‌araformaldehyde (10 min) . The cells were washed twice with 1 X PBS. The cells were incubated in 1 X PBS containing 0.5% BSA + 1 0% goat serum (15 min) to block non-specific protein-protein interactions followed by the incubated with antibody (bs-2060R/AF647, 1μg /1x10^6 cells) for 30 min on ice. Acquisition of 20,000 events was performed.

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    图标文献和实验
    该产品被引用文献

    [IF={{ 4.9 }}] {Ji Woo Im. et al. Stichoposide C and Rhizochalin as Potential Aquaglyceroporin Modulators. MAR DRUGS. 2024 Aug;22(8):335} {IHC} {Mouse}

    [IF={{ 2.7 }}] {Maren E. Buenning. et al. Short-Time Alternating Current Electrical Stimulation and Cell Membrane-Related Components. APPL SCI-BASEL. 2024 Jan;14(2):812} {IF} {Human}

    [IF={{ 2 }}] {Simin Chen. et al. Zengye decoction regulated the expression of aquaporin in colon tissue of rats with constipation through miR-10a-5p targeting Drd2/AC/cAMP axis. HISTOL HISTOPATHOL. 2025 Jan 21:18876} {IF} {Rat}

    [IF={{ 11.3 }}] {Yangchen Han. et al. Sb(Ⅴ) has distinct cellular uptake route and cytotoxic mechanism from Sb(Ⅲ): Anion channel 2 and sulfhydryl binding. J HAZARD MATER. 2025 Sep;495:138820} {WB} {Human}

    [IF={{ 1.935 }}] {Sato K et al. Different Prognostic Implications of Aquaporin-1 and Aquaporin-5 Expression among Different Histological Types of Ovarian Carcinoma.Pathol Oncol Res. 2018 Jul 19.} {IHC} {Human}

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    AQP9 Rabbit pAb(bs-2060R)-50ul/100ul/200ul
    ￥1180 - 2800