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TIMP1 | TIMP-1 Rabbit pAb(bs-0

415R)-50ul/100ul/200ul

价格￥1180 - 2800

品牌Bioss
货号bs-0415R
更新日期2026年10月13日

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规格：
50ul/100ul/200ul

规格：	50ul	产品价格：	￥1180.0
规格：	100ul	产品价格：	￥1980.0
规格：	200ul	产品价格：	￥2800.0

产品编号	bs-0415R
英文名称	TIMP-1 Rabbit pAb
中文名称	金属蛋白酶组织抑制因子-1抗体
英文别名	Clgi; Collagenase inhibitor; EPA; EPO; Erythroid Potentiating Activity; Fibroblast collagenase inhibitor; FLJ90373; HC; Human Collagenase Inhibitor; Metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1 precursor; OTTHUMP00000023214; TIMP 1; TIMP; TIMP metallopeptidase inhibitor 1; TIMP1 protein; Tissue Inhibitor of Metalloproteinase 1; Tissue inhibitor of metalloproteinases; Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor.
产品应用	WB=1:500-2000 Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
交叉反应	Human
抗体来源	Rabbit
免疫原	KLH conjugated synthetic peptide derived from human TIMP-1
亚型	IgG
性状	Liquid
纯化方法	affinity purified by Protein A
克隆类型	Polyclonal
理论分子量	21 kDa
浓度	1mg/ml
储存液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域	Cancer > Invasion/microenvironment > Angiogenesis > ECM enzymes > TIMPs Cancer > Invasion/microenvironment > ECM > Extracellular matrix > TIMPs Cardiovascular > Angiogenesis > Adhesion / ECM > Matrix Metalloproteinases > TIMP Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Metalloprotease inhibitors > TIMPs Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > TIMP1 / TIMP2
亚细胞定位	Secreted.
翻译后修饰	The activity of TIMP1 is dependent on the presence of disulfide bonds.
相似性	Belongs to the protease inhibitor I35 (TIMP) family. _x000D_ Contains 1 NTR domain.
功能	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
保存条件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料	This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq].

应用	推荐稀释比例
{WB}	{1:500-2000}

_x000D_ Sample:
_x000D_ Lane 1: TIMP-1 fusion protein (bs-43009P) 0.2ug
_x000D_ Primary: Anti-TIMP-1(bs-0415R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 21kDa
_x000D_ Observed band size: 25kDa

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