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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul/200ug
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 规格: | 200ug | 产品价格: | ¥5600.0 |
| 产品编号 | bsm-43017M |
| 英文名称 | MMP3 Mouse mAb |
| 中文名称 | 基质金属蛋白酶3单克隆抗体 |
| 英文别名 | MMP3_HUMAN; Stromelysin-1; EC:3.4.24.17; STMY1; SL-1; SL 1; SL1; Matrix metalloproteinase-3(MMP-3); MMP-3; MMP 3; Transin-1; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human MMP-3 protein |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Monoclonal |
| 理论分子量 | 52 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > ECM enzymes > MMPs Cancer > Invasion/microenvironment > ECM > Extracellular matrix > MMPs Cancer > Tumor biomarkers > Enzymes > MMPs Cardiovascular > Angiogenesis > Adhesion / ECM > Matrix Metalloproteinases > MMP Cardiovascular > Atherosclerosis > Thrombosis Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Metalloprotease > MMPs Kits/ Lysates/ Other > Kits > Cell Metabolism Kits > Other Metabolism Assay Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Atherosclerotic proteins ELISA kits Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Cancer proteins ELISA kits Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Developmental proteins ELISA kits Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Protease inhibitors ELISA kits Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > MMP |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix (Probable). |
| 相似性 | Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. |
| 功能 | Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Lane 1: Recombinant human MMP-3 protein
Primary: Anti-MMP3 (bsm-43017M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 60 kDa
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