Sample:MCF-7 (Human) cellLysate at 40 ug
Primary: Anti-PDE4B(bs-9590R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 107kD
Observed band size: 107kD
- ￥1180 - 2800
- Bioss
- bs-9590R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-9590R |
| 英文名称 | PDE4B Rabbit pAb |
| 中文名称 | 磷酸二酯酶4B抗体 |
| 英文别名 | 5''-cyclic phosphodiesterase 4B; cAMP-specific 3''; cAMP-specific 3', 5'-cyclic phosphodiesterase 4B; cAMP-specific 3'5'-cyclic phosphodiesterase 4B; cAMP-specific phosphodiesterase-4 B isoform; DKFZp686F2182; DPDE4; dunce-like phosphodiesterase E4; MGC126529; OTTHUMP00000010652; OTTHUMP00000010653; OTTHUMP00000010654; OTTHUMP00000010656; OTTHUMP00000232365; PDE 4B; PDE IVB; PDE32; Pde4b; PDE4B_HUMAN; PDE4B5; PDEIVB; phosphodiesterase 4B; phosphodiesterase 4B cAMP specific; phosphodiesterase 4B, cAMP specific(phosphodiesterase E4 dunce homolog, Drosophila); phosphodiesterase-4B cAMP-specific(dunce(Drosophila)-homolog); phosphodiesterase-4B cAMP-specific. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PDE4B |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 107 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Second Messenger > Nucleotide Messenger > cAMP |
| 组织特异性 | Expressed in brain, heart, lung and skeletal muscle. |
| 相似性 | Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. |
| 功能 | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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[IF={{ 8.739 }}] {Hailou Zhang. et al. Synergistic effects of two natural compounds of iridoids on rapid antidepressant action by up-regulating hippocampal PACAP signaling. 2022 Mar 31} {WB} {Mouse}
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.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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PDE4B Rabbit pAb(bs-9590R)-50ul/100ul/200ul
￥1180 - 2800
