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- bs-7525R
- 2025年10月24日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7525R |
| 英文名称 | TNMD Rabbit pAb |
| 中文名称 | 腱调蛋白/软骨调节素样1蛋白抗体 |
| 英文别名 | BRICD4; BRICHOS domain containing 4; CHM1 LIKE; CHM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TEM; Tendin; Tenomodulin; Tenomodulin protein; TNMD; TNMD_HUMAN; UNQ771/PRO1565. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TNMD |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 37 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Inhibitors |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 相似性 | Belongs to the chondromodulin-1 family. Contains 1 BRICHOS domain. |
| 功能 | May be an angiogenesis inhibitor. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-TNMD/tenomodulin Polyclonal Antibody, Unconjugated(bs-7525R) 1:200, overnight at 4℃, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Lane 1: Skeletal muscle (Rat) Lysate at 40 ug
Lane 2: Skeletal muscle (Mouse) Lysate at 40 ug
Primary: Anti-TNMD (bs-7525R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
Lane 1: Muscle (Rat) Lysate at 40 ug
Lane 2: HepG2 (Human) Cell Lysate at 30 ug
Lane 3: Heart (Rat) Lysate at 40 ug
Lane 4: SW480 (Human) Cell Lysate at 30 ug
Primary: Anti- TNMD (bs-7525R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 35 kD
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文献和实验[IF={{ 7.01 }}] {Xin Wang. et al. Irreversible Electroporation Improves Tendon Healing in a Rat Model of Collagenase-Induced Achilles Tendinopathy. AM J SPORT MED. ;():} {IHC,IF} {Rat}
[IF={{ 5.88 }}] {Shuai Chen. et al. Tenogenic adipose-derived stem cell sheets with nanoyarn scaffolds for tendon regeneration. Mat Sci Eng C-Mater. 2021 Feb;119:111506} {WB,IHC} {Rabbit}
[IF={{ 5.131 }}] {Kang Lu. et al. Micropattern Silk Fibroin Film Facilitates Tendon Repair In Vivo and Promotes Tenogenic Differentiation of Tendon Stem/Progenitor Cells through the α2β1/FAK/PI3K/AKT Signaling Pathway In Vitro. STEM CELLS INT. 2023 Jan 13;2023:2915826} {IHC} {Rat}
[IF={{ 4.9 }}] {Jae Kyung Lim. et al. Efficacy of Light-Emitting Diode-Mediated Photobiomodulation in Tendon Healing in a Murine Model. INT J MOL SCI. 2025 Jan;26(5):2286} {IHC} {Mouse}
[IF={{ 4.6 }}] {Yao Huang. et al.Biological Augmentation Using Electrospun Constructs with Dual Growth Factor Release for Rotator Cuff Repair.acs applied bio materials.2025 Feb 27.} {Western Blot} {Rat}
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