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AARS2 Rabbit pAb(bs-1603R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1603R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1603R
    英文名称AARS2 Rabbit pAb
    中文名称丙氨酰tRNA合成酶2抗体
    英文别名alanyl tRNA synthetase 2; AARSL; bA444E17.1; Gm89; MT ALARS; MTALARS; AARS 2; AARS2; Alanine tRNA ligase 2 mitochondrial; Alanine tRNA ligase; Alanyl tRNA synthetase 2 mitochondrial; Alanyl tRNA synthetase like; AlaRS; KIAA1270; MGC69820; Probable alanyl tRNA synthetase mitochondrial; RP11-444E17.1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Dog)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human AARS2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量115 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > DNA / RNA > Translation > tRNA synthetase

    亚细胞定位Mitochondrion matrix.
    功能The human alanyl-tRNA synthetase (AlaRS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AlaRS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. Alanyl-tRNA synthetase (AlaRS) catalyzes the ligation of alanine with alanyl-tRNA using ATP.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011].

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Lane 1: Cerebrum (Mouse) Lysate at 40 ug
    Lane 2: Cerebellum (Mouse) Lysate at 40 ug
    Lane 3: Lung (Mouse) Lysate at 40 ug
    Lane 4: Spleen (Mouse) Lysate at 40 ug
    Lane 5: Liver (Mouse) Lysate at 40 ug
    Lane 6: Cerebrum (Rat) Lysate at 40 ug
    Lane 7: Cerebellum (Rat) Lysate at 40 ug
    Lane 8: Lung (Rat) Lysate at 40 ug
    Lane 9: Spleen (Rat) Lysate at 40 ug
    Lane 10: Liver (Rat) Lysate at 40 ug
    Lane 11: 293T (Human) Cell Lysate at 30 ug
    Lane 12: K562 (Human) Cell Lysate at 30 ug
    Primary: Anti-AARS2 (bs-1603R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 107 kD
    Observed band size: 110 kD

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    图标文献和实验
    相关实验
    • Immunochemical Detection of a Fluorophore Derived from the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Lysine

      = NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific

    • 亲和层析凝胶指南

      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

    • 亲和层析凝胶指南

      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

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    ¥1180 - 2800