- ￥480 - 4470
- TargetMol
- USA
- T3078
- 2025年07月13日
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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -3076℃ for several months.
- 英文名：
SGI-1776 free base
- 库存：
详询
- 供应商：
详询
- CAS号：
1025065-69-3
- 规格：
2mg/5mg/10mg/25mg/50mg/1ml/10mM
| 规格： | 2mg | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥960.0 |
| 规格： | 10mg | 产品价格： | ￥1700.0 |
| 规格： | 25mg | 产品价格： | ￥3100.0 |
| 规格： | 50mg | 产品价格： | ￥4470.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥968.0 |
ID：T3078
PURITY：1
Formula：C20H22F3N5O
MolWt：405.42
Appearance：灰色粉末
Solubility：G4DMSO 81 mg/mL;Ethanol 81 mg/mL;Water <1 mg/mL
Bioactivity：SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1.
Status：Experimental
Pathways：JAK/STAT Signaling
Target：Pim inhibitor; FLT3 inhibitor
Receptor：Pim1; FLT3; Pim3;Pim2
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