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- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2398℃ for several months.
- 英文名:
RGB-286638 free base
- 库存:
详询
- 供应商:
详询
- CAS号:
784210-88-4
- 规格:
2mg/5mg/10mg/50mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥949.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1389.0 |
| 规格: | 10mg | 产品价格: | ¥2221.0 |
| 规格: | 50mg | 产品价格: | ¥9229.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥1487.0 |
ID:T2378
PURITY:97%+
Formula:C29H35N7O4
MolWt:545.63
Appearance:黄色粉末
Solubility:G410 mM in DMSO
Bioactivity:RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.
Status:
Pathways:Cell Cycle/Checkpoint
Target:CDK inhibitor
Receptor:cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5
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