- ￥498 - 6300
- TargetMol
- USA
- T3065
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -3063℃ for several months.
- 英文名：
TG101209
- 库存：
详询
- 供应商：
详询
- CAS号：
936091-14-4
- 规格：
2mg/5mg/10mg/25mg/50mg/1ml/10mM
| 规格： | 2mg | 产品价格： | ￥498.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥1080.0 |
| 规格： | 10mg | 产品价格： | ￥1980.0 |
| 规格： | 25mg | 产品价格： | ￥3500.0 |
| 规格： | 50mg | 产品价格： | ￥6300.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥1120.0 |
ID：T3065
PURITY：1
Formula：C26H35N7O2S
MolWt：509.67
Appearance：白色粉末
Solubility：G4DMSO 102 mg/mL;Water <1 mg/mL
Bioactivity：TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.
Status：Undetermined activity
Pathways：Tyrosine Kinase/Adaptors; JAK/STAT Signaling
Target：JAK inhibitor; FLT3 inhibitor; RET inhibitor
Receptor：JAK2;RET;FLT3;JAK3
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文献和实验Transgenic Mouse and Gene Targeting Facility Tg 008 Southern Blotting Materials and Equipment Hybaid hybridization oven (ISC BioExpress,H-9250) Vacuum oven (VWR,52201-218) Ludlum Geiger Counter Radiation Shields and lock box (from various
Transgenic Mouse and Gene Targeting Facility Tg 008 Southern Blotting Materials and Equipment Hybaid hybridization oven (ISC BioExpress, H-9250) Vacuum oven (VWR, 52201-218) Ludlum Geiger Counter Radiation Shields
APP-Based Transgenic Models: The Tg2576 Model
, economic, and personal impact. In 1996, Karen Hsiao and colleagues showed that transgenic mice, which overexpress a human APP cDNA transgene from a Swedish family whose members showed early onset, familial AD (Tg2576 mice) were cognitively impaired
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