- ￥460 - 3939
- TargetMol
- USA
- T2157
- 2025年07月10日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2184℃ for several months.
- 英文名：
Histone Deacetylase Inhibitor III
- 库存：
详询
- 供应商：
详询
- CAS号：
251456-60-7
- 规格：
1mg/5mg/10mg/25mg/50mg/1ml/10mM
| 规格： | 1mg | 产品价格： | ￥460.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥727.0 |
| 规格： | 10mg | 产品价格： | ￥1088.0 |
| 规格： | 25mg | 产品价格： | ￥2312.0 |
| 规格： | 50mg | 产品价格： | ￥3939.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥757.0 |
ID：T2157
PURITY：97%+
Formula：C16H25N3O3
MolWt：307.39
Appearance：白色粉末
Solubility：G4200 mM in DMSO and 10 mM in ethanol
Bioactivity：M344 is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.
Status：
Pathways：Chromatin/Epigenetic
Target：HDAC inhibitor
Receptor：HDACs
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文献和实验Histone Deacetylase Activity Assay
Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl groups from the ɛ-amino groups of conserved lysine residues in the amino terminal tail of histones. In humans, there are 18 potential deacetylase enzymes
Analysis of Checkpoint Responses to Histone Deacetylase Inhibitors
Cell cycle checkpoints respond to a wide range of stresses to prevent compromise to the integrity of the cell. The best studied checkpoints are those induced by genotoxic agents that cause DNA damage. Histone deacetylase inhibitors
of pluripotent P19 cells into skeletal muscle lineage by using histone deacetylase inhibitor, valproic acid and the ligand of retinoic acid receptor, all-trans retinoic acid.
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