Peptide sequence around phosphorylation site of tyrosine 705 (A-P-Y(p)-L-K) derived from Human STAT3.
规格:
50ul/100ul
规格:
50ul
产品价格:
询价
规格:
100ul
产品价格:
询价
Product Name: STAT3(Phospho-Tyr705) Antibody
Host Species: Rabbit
Clonality: Polyclonal
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Applications: WB IHC IF
Species Reactivity: Hu Ms Rt
Specificity: The antibody detects endogenous level of STAT3 only when phosphorylated at tyrosine 705.
Immunogen Type: Peptide-KLH
Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 705 (A-P-Y(p)-L-K) derived from Human STAT3.
Target Name: STAT3
Modification: Phospho
Alternative Names: APRF; Acute-phase response factor; HIES
Formulation: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Images:
Western blot analysis of extracts from Hela cells untreated or treated with IFN a using STAT3(Phospho-Tyr705) Antibody #11045.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (Phospho-Tyr705) Antibody #11045 (left) or the same antibody preincubated with blocking peptide #51045 (right).
Immunohistochemical analysis of paraffin-embedded human Lung carcinoma tissue using STAT3 (Phospho-Tyr705) Antibody #11045.
Immunofluorescence staining of methanol-fixed MEF cells untreated or treated with IFN using STAT3 (Phospho-Tyr705) Antibody #11045.
Knockdown of CTCF reduces the binding of EZH2 and affects the methylation of the SOCS3 promoter in hepatocellular carcinoma.In Int J Biochem Cell Biol on 2020 Mar; by Wei L, Liu Q, et al..PMID: 31917284,, (2020), PMID: 31917284
Effect of STAT3 decoy oligodeoxynucleotides mediated by ultrasound-targeted microbubbles combIned with ultrasound on the growth of squamous cell carcInoma of the esophagus. In Oncol Lett on 2019 Feb by Zhang Y, Zhang M, et al..PMID:30675281,, (2019), PMID: 30675281
A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861,, (2019), PMID: 31594861
Detection of promoter methylation status of suppressor of cytokine signaling 3 (SOCS3) in tissue and plasma from Chinese patients with different hepatic diseases.In Clin Exp Med. On 2018 Feb by Wei L, Huang Y et al..PMID:28951980,, (2018), PMID: 28951980